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Browse result for Neddylation
※ introduction Neddylation (also NEDDylation) is the process by which the ubiquitin-like protein NEDD8 is conjugated to its target proteins. This process is analogous to ubiquitination, although it relies on its own E1 and E2 enzymes. No NEDD8-specific E3 has yet been identified and it is possible that the Neddylation system relies on E3 ligases with dual specificity.
Reference
Wiki: Neddylation
Reference
Wiki: Neddylation
| PTMD ID | UniProt Accession | Entrez ID | Gene Name | Protein Name | Organism |
|---|---|---|---|---|---|
| PTMD00006 | P04637 | 7157 | TP53 | Cellular tumor antigen p53 | Homo sapiens |
| PTMD00886 | P05067 | 351 | APP | Amyloid-beta precursor protein precursor protein) [Cleaved into: N-APP; Soluble APP-alpha ; Soluble APP-beta ; C99 ; Amyloid-beta protein 42 ; Amyloid-beta protein 40 ; C83 ; P3; P3; C80; Gamma-secretase C-terminal fragment 59 ) ); Gamma-secretase C-terminal fragment 57 ) ); Gamma-secretase C-terminal fragment 50 ) ); C31] | Homo sapiens |
| PTMD00254 | P37173 | 7048 | TGFBR2 | TGF-beta receptor type-2 | Homo sapiens |
| PTMD00233 | Q93034 | 8065 | CUL5 | Cullin-5 | Homo sapiens |
| PTMD00231 | Q13616 | 8454 | CUL1 | Cullin-1 | Homo sapiens |
| PTMD00232 | P36956 | 6720 | SREBF1 | Sterol regulatory element-binding protein 1 [Cleaved into: Processed sterol regulatory element-binding protein 1 ] | Homo sapiens |
| PTMD00234 | O14733 | 5609 | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 | Homo sapiens |
| PTMD00021 | P12931 | 6714 | SRC | Proto-oncogene tyrosine-protein kinase Src | Homo sapiens |
| PTMD00468 | O43818 | 9136 | RRP9 | U3 small nucleolar RNA-interacting protein 2 | Homo sapiens |
| PTMD00524 | P10276 | 5914 | RARA | Retinoic acid receptor alpha | Homo sapiens |
| PTMD00660 | Q06124 | 5781 | PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 | Homo sapiens |
| PTMD00333 | Q15717 | 1994 | ELAVL1 | ELAV-like protein 1 | Homo sapiens |
| PTMD00093 | P19474 | 6737 | TRIM21 | E3 ubiquitin-protein ligase TRIM21 ) | Homo sapiens |
| PTMD00228 | Q13547 | 3065 | HDAC1 | Histone deacetylase 1 | Homo sapiens |
| PTMD00011 | Q16665 | 3091 | HIF1A | Hypoxia-inducible factor 1-alpha | Homo sapiens |
| PTMD01015 | P62877 | 9978 | RBX1 | E3 ubiquitin-protein ligase RBX1 [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed ] | Homo sapiens |
| PTMD01014 | P61081 | 9040 | UBE2M | NEDD8-conjugating enzyme Ubc12 | Homo sapiens |
| PTMD00020 | P60484 | 5728 | PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | Homo sapiens |
| PTMD00002 | P38936 | 1026 | CDKN1A | Cyclin-dependent kinase inhibitor 1 | Homo sapiens |
| PTMD00589 | P37231 | 5468 | PPARG | Peroxisome proliferator-activated receptor gamma | Homo sapiens |
| PTMD01113 | P84103 | 6428 | SRSF3 | Serine/arginine-rich splicing factor 3 | Homo sapiens |
| PTMD01391 | Q8CH77 | 21569 | Nav1 | Neuron navigator 1 | Mus musculus |