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Browse result for Up-regulation in Phosphorylation

※ introduction

    In biochemistry, phosphorylation is the attachment of a phosphate group to a molecule or an ion. This process and its inverse, dephosphorylation, are common in biology. Protein phosphorylation often activates (or deactivates) many enzymes.

Reference
Wiki: Phosphorylation


PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD00006P046377157
TP53
Cellular tumor antigen p53
Homo sapiens
PTMD00007P352221499
CTNNB1
Catenin beta-1
Homo sapiens
PTMD00016O146411856
DVL2
Segment polarity protein dishevelled homolog DVL-2
Homo sapiens
PTMD00017P412217474
WNT5A
Protein Wnt-5a
Homo sapiens
PTMD00018Q166447867
MAPKAPK3
MAP kinase-activated protein kinase 3
Homo sapiens
PTMD00020P604845728
PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Homo sapiens
PTMD00021P129316714
SRC
Proto-oncogene tyrosine-protein kinase Src
Homo sapiens
PTMD00022P4693710413
YAP1
Transcriptional coactivator YAP1
Homo sapiens
PTMD00031P465271027
CDKN1B
Cyclin-dependent kinase inhibitor 1B
Homo sapiens
PTMD00038P311525596
MAPK4
Mitogen-activated protein kinase 4
Homo sapiens
PTMD00039P565249759
HDAC4
Histone deacetylase 4
Homo sapiens
PTMD00040P407636774
STAT3
Signal transducer and activator of transcription 3
Homo sapiens
PTMD00041P498412932
GSK3B
Glycogen synthase kinase-3 beta
Homo sapiens
PTMD00042P053623383
ICAM1
Intercellular adhesion molecule 1
Homo sapiens
PTMD00043P046262064
ERBB2
Receptor tyrosine-protein kinase erbB-2
Homo sapiens
PTMD00044Q009874193
MDM2
E3 ubiquitin-protein ligase Mdm2
Homo sapiens
PTMD00045Q9Y2811073
CFL2
Cofilin-2
Homo sapiens
PTMD00046O1504223350
U2SURP
U2 snRNP-associated SURP motif-containing protein
Homo sapiens
PTMD00047O755814040
LRP6
Low-density lipoprotein receptor-related protein 6
Homo sapiens
PTMD00048P153117430
EZR
Ezrin
Homo sapiens
PTMD00049P31749207
AKT1
RAC-alpha serine/threonine-protein kinase
Homo sapiens
PTMD00050O958636615
SNAI1
Zinc finger protein SNAI1
Homo sapiens
PTMD00051Q166356901
TAFAZZIN
Tafazzin
Homo sapiens
PTMD00052Q995589020
MAP3K14
Mitogen-activated protein kinase kinase kinase 14
Homo sapiens
PTMD00053Q9BY4483939
EIF2A
Eukaryotic translation initiation factor 2A [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed]
Homo sapiens
PTMD00055P047923315
HSPB1
Heat shock protein beta-1
Homo sapiens
PTMD00056P484316657
SOX2
Transcription factor SOX-2
Homo sapiens
PTMD00058P273615595
MAPK3
Mitogen-activated protein kinase 3
Homo sapiens
PTMD00059Q9UQM7815
CAMK2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Homo sapiens
PTMD00060O152645603
MAPK13
Mitogen-activated protein kinase 13
Homo sapiens
PTMD00061O606743717
JAK2
Tyrosine-protein kinase JAK2
Homo sapiens
PTMD00062O433538767
RIPK2
Receptor-interacting serine/threonine-protein kinase 2
Homo sapiens
PTMD00063P491167182
NR2C2
Nuclear receptor subfamily 2 group C member 2
Homo sapiens
PTMD00064Q142472017
CTTN
Src substrate cortactin
Homo sapiens
PTMD00065P284825594
MAPK1
Mitogen-activated protein kinase 1
Homo sapiens
PTMD00066O435242309
FOXO3
Forkhead box protein O3
Homo sapiens
PTMD00067P005331956
EGFR
Epidermal growth factor receptor
Homo sapiens
PTMD00068P423452475
MTOR
Serine/threonine-protein kinase mTOR
Homo sapiens
PTMD00069Q080502305
FOXM1
Forkhead box protein M1
Homo sapiens
PTMD00070Q9HBJ757663
USP29
Ubiquitin carboxyl-terminal hydrolase 29
Homo sapiens
PTMD00071P179363486
IGFBP3
Insulin-like growth factor-binding protein 3
Homo sapiens
PTMD00072Q9GZN260436
TGIF2
Homeobox protein TGIF2
Homo sapiens
PTMD00073P546195571
PRKAG1
5'-AMP-activated protein kinase subunit gamma-1
Homo sapiens
PTMD00075P064005925
RB1
Retinoblastoma-associated protein
Homo sapiens
PTMD00076Q6PJF579651
RHBDF2
Inactive rhomboid protein 2
Homo sapiens
PTMD00087P61586387
RHOA
Transforming protein RhoA
Homo sapiens
PTMD00088P179476688
SPI1
Transcription factor PU.1
Homo sapiens
PTMD00089Q13950860
RUNX2
Runt-related transcription factor 2
Homo sapiens
PTMD00094Q162364780
NFE2L2
Nuclear factor erythroid 2-related factor 2
Homo sapiens
PTMD00131P07355302
ANXA2
Annexin A2
Homo sapiens
PTMD00160Q042065970
RELA
Transcription factor p65
Homo sapiens
PTMD00168P054123725
JUN
Transcription factor Jun
Homo sapiens
PTMD00184P621365499
PPP1CA
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Homo sapiens
PTMD00201P627536194
RPS6
Small ribosomal subunit protein eS6
Homo sapiens
PTMD00202P085814233
MET
Hepatocyte growth factor receptor
Homo sapiens
PTMD00207O754602081
ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1 [Includes: Serine/threonine-protein kinase ; Endoribonuclease ]
Homo sapiens
PTMD00210Q053975747
PTK2
Focal adhesion kinase 1
Homo sapiens
PTMD00211Q9UHD229110
TBK1
Serine/threonine-protein kinase TBK1
Homo sapiens
PTMD00213P422246772
STAT1
Signal transducer and activator of transcription 1-alpha/beta
Homo sapiens
PTMD00219P146185315
PKM
Pyruvate kinase PKM
Homo sapiens
PTMD00225P6843183508
H3C1
Histone H3.1
Homo sapiens
PTMD00235P359683791
KDR
Vascular endothelial growth factor receptor 2
Homo sapiens
PTMD00256Q132334214
MAP3K1
Mitogen-activated protein kinase kinase kinase 1
Homo sapiens
PTMD00257Q9Y5W310365
KLF2
Krueppel-like factor 2
Homo sapiens
PTMD00258O149203551
IKBKB
Inhibitor of nuclear factor kappa-B kinase subunit beta
Homo sapiens
PTMD00259Q135411978
EIF4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1
Homo sapiens
PTMD00260P47756832
CAPZB
F-actin-capping protein subunit beta
Homo sapiens
PTMD00261P52907829
CAPZA1
F-actin-capping protein subunit alpha-1
Homo sapiens
PTMD00262P191745335
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Homo sapiens
PTMD00263O949724591
TRIM37
E3 ubiquitin-protein ligase TRIM37
Homo sapiens
PTMD00267P490235829
PXN
Paxillin
Homo sapiens
PTMD00268Q8TD0822568
MAPK15
Mitogen-activated protein kinase 15
Homo sapiens
PTMD00269Q8NFG420116
FLCN
Folliculin
Homo sapiens
PTMD00270Q129654643
MYO1E
Unconventional myosin-Ie
Homo sapiens
PTMD00274P055563688
ITGB1
Integrin beta-1
Homo sapiens
PTMD00297P198384790
NFKB1
Nuclear factor NF-kappa-B p105 subunit [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Homo sapiens
PTMD00305P040495894
RAF1
RAF proto-oncogene serine/threonine-protein kinase
Homo sapiens
PTMD00321Q157964087
SMAD2
Mothers against decapentaplegic homolog 2
Homo sapiens
PTMD00332P080693480
IGF1R
Insulin-like growth factor 1 receptor [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Homo sapiens
PTMD00338P106364137
MAPT
Microtubule-associated protein tau
Homo sapiens
PTMD00388Q1328310146
G3BP1
Ras GTPase-activating protein-binding protein 1
Homo sapiens
PTMD00392Q089995934
RBL2
Retinoblastoma-like protein 2
Homo sapiens
PTMD00404P235881975
EIF4B
Eukaryotic translation initiation factor 4B
Homo sapiens
PTMD00466O435838562
DENR
Density-regulated protein
Homo sapiens
PTMD00508P051981965
EIF2S1
Eukaryotic translation initiation factor 2 subunit 1
Homo sapiens
PTMD00510P062393932
LCK
Tyrosine-protein kinase Lck
Homo sapiens
PTMD00525P10415596
BCL2
Apoptosis regulator Bcl-2
Homo sapiens
PTMD00548P1885022926
ATF6
Cyclic AMP-dependent transcription factor ATF-6 alpha [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 alpha]
Homo sapiens
PTMD00571P293171969
EPHA2
Ephrin type-A receptor 2
Homo sapiens
PTMD00587P365075605
MAP2K2
Dual specificity mitogen-activated protein kinase kinase 2
Homo sapiens
PTMD00598P459835599
MAPK8
Mitogen-activated protein kinase 8
Homo sapiens
PTMD00599P459856416
MAP2K4
Dual specificity mitogen-activated protein kinase kinase 4
Homo sapiens
PTMD00621P569459564
BCAR1
Breast cancer anti-estrogen resistance protein 1
Homo sapiens
PTMD00645Q027505604
MAP2K1
Dual specificity mitogen-activated protein kinase kinase 1
Homo sapiens
PTMD00723Q6PKG023367
LARP1
La-related protein 1
Homo sapiens
PTMD00727Q70EK915888
USP51
Ubiquitin carboxyl-terminal hydrolase 51
Homo sapiens
PTMD00762Q92934572
BAD
Bcl2-associated agonist of cell death
Homo sapiens
PTMD00771Q96I2584991
RBM17
Splicing factor 45
Homo sapiens
PTMD00784Q997174090
SMAD5
Mothers against decapentaplegic homolog 5
Homo sapiens
PTMD00887P067301977
EIF4E
Eukaryotic translation initiation factor 4E
Homo sapiens
PTMD00906P422266778
STAT6
Signal transducer and activator of transcription 6
Homo sapiens
PTMD00941P422296776
STAT5A
Signal transducer and activator of transcription 5A
Homo sapiens
PTMD00943P234436198
RPS6KB1
Ribosomal protein S6 kinase beta-1
Homo sapiens
PTMD00945Q165391432
MAPK14
Mitogen-activated protein kinase 14
Homo sapiens
PTMD00946P355683667
IRS1
Insulin receptor substrate 1
Homo sapiens
PTMD00947Q011306427
SRSF2
Serine/arginine-rich splicing factor 2
Homo sapiens
PTMD00960P218602065
ERBB3
Receptor tyrosine-protein kinase erbB-3
Homo sapiens
PTMD00968Q9UPY323405
DICER1
Endoribonuclease Dicer
Homo sapiens
PTMD01001Q132242904
GRIN2B
Glutamate receptor ionotropic, NMDA 2B
Homo sapiens
PTMD01006O9525111143
KAT7
Histone acetyltransferase KAT7
Homo sapiens
PTMD01007O147571111
CHEK1
Serine/threonine-protein kinase Chk1
Homo sapiens
PTMD01008O432947041
TGFB1I1
Transforming growth factor beta-1-induced transcript 1 protein
Homo sapiens
PTMD01009P218022263
FGFR2
Fibroblast growth factor receptor 2
Homo sapiens
PTMD01010Q96TA164855
NIBAN2
Protein Niban 2
Homo sapiens
PTMD01074P195255610
EIF2AK2
Interferon-induced, double-stranded RNA-activated protein kinase
Homo sapiens
PTMD01079P293536464
SHC1
SHC-transforming protein 1
Homo sapiens
PTMD01097P434056850
SYK
Tyrosine-protein kinase SYK
Homo sapiens
PTMD01201P234583716
JAK1
Tyrosine-protein kinase JAK1
Homo sapiens
PTMD01205Q019734919
ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1
Homo sapiens
PTMD01207Q141649641
IKBKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
Homo sapiens
PTMD01219Q049124486
MST1R
Macrophage-stimulating protein receptor [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]
Homo sapiens
PTMD01222P051063690
ITGB3
Integrin beta-3
Homo sapiens
PTMD01223Q153343996
LLGL1
Lethal giant larvae protein homolog 1
Homo sapiens
PTMD01293P203091131
CHRM3
Muscarinic acetylcholine receptor M3
Homo sapiens
PTMD01300Q056555580
PRKCD
Protein kinase C delta type [Cleaved into: Protein kinase C delta type regulatory subunit; Protein kinase C delta type catalytic subunit ]
Homo sapiens
PTMD01302P057715579
PRKCB
Protein kinase C beta type
Homo sapiens
PTMD01305P051096279
S100A8
Protein S100-A8
Homo sapiens
PTMD01307P461091399
CRKL
Crk-like protein
Homo sapiens
PTMD01309Q9C00022861
NLRP1
NACHT, LRR and PYD domains-containing protein 1 [Cleaved into: NACHT, LRR and PYD domains-containing protein 1, C-terminus ; NACHT, LRR and PYD domains-containing protein 1, N-terminus ]
Homo sapiens
PTMD01311Q021565581
PRKCE
Protein kinase C epsilon type
Homo sapiens
PTMD01313P6280730178
H2BC4
Histone H2B type 1-C/E/F/G/I
Homo sapiens
PTMD01314Q9252953358
SHC3
SHC-transforming protein 3
Homo sapiens
PTMD01349P15848411
ARSB
Arylsulfatase B
Homo sapiens
PTMD01375Q142108581
LY6D
Lymphocyte antigen 6D
Homo sapiens
PTMD01389Q146533661
IRF3
Interferon regulatory factor 3
Homo sapiens
PTMD00074P1281315370
Nr4a1
Nuclear receptor subfamily 4 group A member 1
Mus musculus
PTMD00907P4222720848
Stat3
Signal transducer and activator of transcription 3
Mus musculus
PTMD01096P4223020850
Stat5a
Signal transducer and activator of transcription 5A
Mus musculus
PTMD01117Q0127913649
Egfr
Epidermal growth factor receptor
Mus musculus
PTMD01199P0864424525
Kras
GTPase KRas [Cleaved into: GTPase KRas, N-terminally processed]
Rattus norvegicus
PTMD01200P1134524703
Raf1
RAF proto-oncogene serine/threonine-protein kinase
Rattus norvegicus
PTMD01211Q6ZWX613665
Eif2s1
Eukaryotic translation initiation factor 2 subunit 1
Mus musculus
PTMD01287Q6087613685
Eif4ebp1
Eukaryotic translation initiation factor 4E-binding protein 1
Mus musculus
PTMD01316P1866650685
Myl12b
Myosin regulatory light chain 12B
Rattus norvegicus
PTMD01340P3557025467
Irs1
Insulin receptor substrate 1
Rattus norvegicus
PTMD01347P2268212402
Cbl
E3 ubiquitin-protein ligase CBL
Mus musculus
PTMD01351P6275529304
Rps6
Small ribosomal subunit protein eS6
Rattus norvegicus
PTMD01358P4783839614
RPS6
Small ribosomal subunit protein eS6
Gallus gallus
PTMD01359E9PT59
Arhgef5
Rho guanine nucleotide exchange factor 5
Rattus norvegicus
PTMD01362Q66H76
Pxn
Paxillin
Rattus norvegicus
PTMD01364P6275420104
Rps6
Small ribosomal subunit protein eS6
Mus musculus
PTMD01365P4944524678
Ptpn7
Tyrosine-protein phosphatase non-receptor type 7
Rattus norvegicus
PTMD01390Q9WV6056637
Gsk3b
Glycogen synthase kinase-3 beta
Mus musculus