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Browse result for Up-regulation in Neddylation
※ introduction Neddylation (also NEDDylation) is the process by which the ubiquitin-like protein NEDD8 is conjugated to its target proteins. This process is analogous to ubiquitination, although it relies on its own E1 and E2 enzymes. No NEDD8-specific E3 has yet been identified and it is possible that the Neddylation system relies on E3 ligases with dual specificity.
Reference
Wiki: Neddylation
Reference
Wiki: Neddylation
| PTMD ID | UniProt Accession | Entrez ID | Gene Name | Protein Name | Organism |
|---|---|---|---|---|---|
| PTMD00002 | P38936 | 1026 | CDKN1A | Cyclin-dependent kinase inhibitor 1 | Homo sapiens |
| PTMD00006 | P04637 | 7157 | TP53 | Cellular tumor antigen p53 | Homo sapiens |
| PTMD00020 | P60484 | 5728 | PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | Homo sapiens |
| PTMD00093 | P19474 | 6737 | TRIM21 | E3 ubiquitin-protein ligase TRIM21 ) | Homo sapiens |
| PTMD00231 | Q13616 | 8454 | CUL1 | Cullin-1 | Homo sapiens |
| PTMD00232 | P36956 | 6720 | SREBF1 | Sterol regulatory element-binding protein 1 [Cleaved into: Processed sterol regulatory element-binding protein 1 ] | Homo sapiens |
| PTMD00233 | Q93034 | 8065 | CUL5 | Cullin-5 | Homo sapiens |
| PTMD00234 | O14733 | 5609 | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 | Homo sapiens |
| PTMD00333 | Q15717 | 1994 | ELAVL1 | ELAV-like protein 1 | Homo sapiens |
| PTMD00589 | P37231 | 5468 | PPARG | Peroxisome proliferator-activated receptor gamma | Homo sapiens |
| PTMD01014 | P61081 | 9040 | UBE2M | NEDD8-conjugating enzyme Ubc12 | Homo sapiens |
| PTMD01113 | P84103 | 6428 | SRSF3 | Serine/arginine-rich splicing factor 3 | Homo sapiens |