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Browse result for Up-regulation in Gamma-carboxylation

※ introduction

    Carboxyglutamic acid (or the conjugate base, carboxyglutamate), is an uncommon amino acid introduced into proteins by a post-translational carboxylation of glutamic acid residues. This modification is found, for example, in clotting factors and other proteins of the coagulation cascade. This modification introduces an affinity for calcium ions. In the blood coagulation cascade, vitamin K is required to introduce ¦Ã-carboxylation of clotting factors II, VII, IX, X and protein Z.

Reference
Wiki: Gamma-carboxylation



PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD00980P02818632
BGLAP
Osteocalcin
Homo sapiens
PTMD01377Q6159214456
Gas6
Growth arrest-specific protein 6
Mus musculus