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Browse result for Disruption in Neddylation

※ introduction

    Neddylation (also NEDDylation) is the process by which the ubiquitin-like protein NEDD8 is conjugated to its target proteins. This process is analogous to ubiquitination, although it relies on its own E1 and E2 enzymes. No NEDD8-specific E3 has yet been identified and it is possible that the Neddylation system relies on E3 ligases with dual specificity.

Reference
Wiki: Neddylation


PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD00006P046377157
TP53
Cellular tumor antigen p53
Homo sapiens
PTMD00254P371737048
TGFBR2
TGF-beta receptor type-2
Homo sapiens
PTMD00886P05067351
APP
Amyloid-beta precursor protein precursor protein) [Cleaved into: N-APP; Soluble APP-alpha ; Soluble APP-beta ; C99 ; Amyloid-beta protein 42 ; Amyloid-beta protein 40 ; C83 ; P3; P3; C80; Gamma-secretase C-terminal fragment 59 ) ); Gamma-secretase C-terminal fragment 57 ) ); Gamma-secretase C-terminal fragment 50 ) ); C31]
Homo sapiens