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Browse result for Disruption in Arginine methylation
※ introduction Arginine methylation is a prevalent post-translational modification found on both nuclear and cytoplasmic proteins. The methylation of arginine residues is catalyzed by the protein arginine Nmethyltransferase (PRMT) family of enzymes. Proteins that are arginine methylated are involved in a number of different cellular processes, including transcriptional regulation, RNA metabolism and DNA damage repair (Bedford and Richard, 2005). Most PRMTs methylate glycine- and arginine-rich patches (GAR motifs) within their substrates.
Reference
Wiki: Arginine methylation
Reference
Wiki: Arginine methylation
| PTMD ID | UniProt Accession | Entrez ID | Gene Name | Protein Name | Organism |
|---|---|---|---|---|---|
| PTMD00456 | O14744 | 10419 | PRMT5 | Protein arginine N-methyltransferase 5 [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed] | Homo sapiens |
| PTMD01525 | P15924 | 1832 | DSP | Desmoplakin | Homo sapiens |
| PTMD01580 | P29033 | 2706 | GJB2 | Gap junction beta-2 protein | Homo sapiens |
| PTMD01335 | O88508 | 13435 | Dnmt3a | DNA -methyltransferase 3A | Mus musculus |
