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Browse result for Down-regulation in Tyrosine phosphorylation
※ introduction Tyrosine phosphorylation is the addition of a phosphate (PO43?) group to the amino acid tyrosine on a protein. It is one of the main types of protein phosphorylation. This transfer is made possible through enzymes called tyrosine kinases. Tyrosine phosphorylation is a key step in signal transduction and the regulation of enzymatic activity.
Reference
Wiki: Tyrosine phosphorylation
Reference
Wiki: Tyrosine phosphorylation
| PTMD ID | UniProt Accession | Entrez ID | Gene Name | Protein Name | Organism |
|---|---|---|---|---|---|
| PTMD00021 | P12931 | 6714 | SRC | Proto-oncogene tyrosine-protein kinase Src | Homo sapiens |
| PTMD00022 | P46937 | 10413 | YAP1 | Transcriptional coactivator YAP1 | Homo sapiens |
| PTMD00040 | P40763 | 6774 | STAT3 | Signal transducer and activator of transcription 3 | Homo sapiens |
| PTMD00041 | P49841 | 2932 | GSK3B | Glycogen synthase kinase-3 beta | Homo sapiens |
| PTMD00043 | P04626 | 2064 | ERBB2 | Receptor tyrosine-protein kinase erbB-2 | Homo sapiens |
| PTMD00058 | P27361 | 5595 | MAPK3 | Mitogen-activated protein kinase 3 | Homo sapiens |
| PTMD00067 | P00533 | 1956 | EGFR | Epidermal growth factor receptor | Homo sapiens |
| PTMD00122 | Q13043 | 6789 | STK4 | Serine/threonine-protein kinase 4 [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit ; Serine/threonine-protein kinase 4 18kDa subunit ] | Homo sapiens |
| PTMD00202 | P08581 | 4233 | MET | Hepatocyte growth factor receptor | Homo sapiens |
| PTMD00210 | Q05397 | 5747 | PTK2 | Focal adhesion kinase 1 | Homo sapiens |
| PTMD00213 | P42224 | 6772 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | Homo sapiens |
| PTMD00235 | P35968 | 3791 | KDR | Vascular endothelial growth factor receptor 2 | Homo sapiens |
| PTMD00275 | Q9NQ25 | 57823 | SLAMF7 | SLAM family member 7 | Homo sapiens |
| PTMD00506 | P05023 | 476 | ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha-1 /K ATPase alpha-1 subunit) | Homo sapiens |
| PTMD00510 | P06239 | 3932 | LCK | Tyrosine-protein kinase Lck | Homo sapiens |
| PTMD00530 | P11413 | 2539 | G6PD | Glucose-6-phosphate 1-dehydrogenase | Homo sapiens |
| PTMD00552 | P19429 | 7137 | TNNI3 | Troponin I, cardiac muscle | Homo sapiens |
| PTMD00571 | P29317 | 1969 | EPHA2 | Ephrin type-A receptor 2 | Homo sapiens |
| PTMD00649 | Q03135 | 857 | CAV1 | Caveolin-1 | Homo sapiens |
| PTMD00689 | Q14790 | 841 | CASP8 | Caspase-8 [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] | Homo sapiens |
| PTMD00710 | Q3V6T2 | 55704 | CCDC88A | Girdin | Homo sapiens |
| PTMD00778 | Q96QV6 | 22161 | H2AC1 | Histone H2A type 1-A | Homo sapiens |
| PTMD00801 | Q9HAP2 | 22877 | MLXIP | MLX-interacting protein | Homo sapiens |
| PTMD00935 | Q9NPH5 | 50507 | NOX4 | NADPH oxidase 4 H-oxidase) | Homo sapiens |
| PTMD00941 | P42229 | 6776 | STAT5A | Signal transducer and activator of transcription 5A | Homo sapiens |
| PTMD00945 | Q16539 | 1432 | MAPK14 | Mitogen-activated protein kinase 14 | Homo sapiens |
| PTMD00960 | P21860 | 2065 | ERBB3 | Receptor tyrosine-protein kinase erbB-3 | Homo sapiens |
| PTMD01070 | P16104 | 3014 | H2AX | Histone H2AX | Homo sapiens |
| PTMD01079 | P29353 | 6464 | SHC1 | SHC-transforming protein 1 | Homo sapiens |
| PTMD01192 | Q9UM73 | 238 | ALK | ALK tyrosine kinase receptor | Homo sapiens |
| PTMD01244 | P67775 | 5515 | PPP2CA | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | Homo sapiens |
| PTMD01343 | P15498 | 7409 | VAV1 | Proto-oncogene vav | Homo sapiens |
| PTMD01431 | O60500 | 4868 | NPHS1 | Nephrin | Homo sapiens |
| PTMD01475 | P06213 | 3643 | INSR | Insulin receptor [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta] | Homo sapiens |
| PTMD01528 | P16234 | 5156 | PDGFRA | Platelet-derived growth factor receptor alpha | Homo sapiens |
| PTMD01641 | P49789 | 2272 | FHIT | Bis-triphosphatase | Homo sapiens |
| PTMD01694 | P68032 | 70 | ACTC1 | Actin, alpha cardiac muscle 1 [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form] | Homo sapiens |
| PTMD01722 | Q04760 | 2739 | GLO1 | Lactoylglutathione lyase | Homo sapiens |
| PTMD01743 | Q13480 | 2549 | GAB1 | GRB2-associated-binding protein 1 | Homo sapiens |
| PTMD01866 | Q96RI1 | 9971 | NR1H4 | Bile acid receptor | Homo sapiens |
| PTMD01914 | Q9NZC7 | 51741 | WWOX | WW domain-containing oxidoreductase | Homo sapiens |
| PTMD01088 | P35235 | 19247 | Ptpn11 | Tyrosine-protein phosphatase non-receptor type 11 | Mus musculus |
| PTMD01243 | P63086 | 11659 | Mapk1 | Mitogen-activated protein kinase 1 | Rattus norvegicus |
| PTMD01541 | P19139 | 11654 | Csnk2a1 | Casein kinase II subunit alpha | Rattus norvegicus |
| PTMD01548 | P21708 | 50689 | Mapk3 | Mitogen-activated protein kinase 3 | Rattus norvegicus |
| PTMD01557 | P24062 | 25718 | Igf1r | Insulin-like growth factor 1 receptor [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] | Rattus norvegicus |
| PTMD01605 | P35546 | 19713 | Ret | Proto-oncogene tyrosine-protein kinase receptor Ret [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] | Mus musculus |
| PTMD01613 | P35918 | 16542 | Kdr | Vascular endothelial growth factor receptor 2 | Mus musculus |
| PTMD01638 | P49185 | 11655 | Mapk8 | Mitogen-activated protein kinase 8 | Rattus norvegicus |
| PTMD01698 | P70313 | 18127 | Nos3 | Nitric oxide synthase 3 | Mus musculus |
| PTMD01791 | Q60598 | 13043 | Cttn | Src substrate cortactin | Mus musculus |
| PTMD01919 | Q9R044 | 64563 | Nphs1 | Nephrin | Rattus norvegicus |