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Browse result for Down-regulation in Neddylation
※ introduction Neddylation (also NEDDylation) is the process by which the ubiquitin-like protein NEDD8 is conjugated to its target proteins. This process is analogous to ubiquitination, although it relies on its own E1 and E2 enzymes. No NEDD8-specific E3 has yet been identified and it is possible that the Neddylation system relies on E3 ligases with dual specificity.
Reference
Wiki: Neddylation
Reference
Wiki: Neddylation
| PTMD ID | UniProt Accession | Entrez ID | Gene Name | Protein Name | Organism |
|---|---|---|---|---|---|
| PTMD00011 | Q16665 | 3091 | HIF1A | Hypoxia-inducible factor 1-alpha | Homo sapiens |
| PTMD00021 | P12931 | 6714 | SRC | Proto-oncogene tyrosine-protein kinase Src | Homo sapiens |
| PTMD00228 | Q13547 | 3065 | HDAC1 | Histone deacetylase 1 | Homo sapiens |
| PTMD00254 | P37173 | 7048 | TGFBR2 | TGF-beta receptor type-2 | Homo sapiens |
| PTMD00660 | Q06124 | 5781 | PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 | Homo sapiens |
| PTMD01015 | P62877 | 9978 | RBX1 | E3 ubiquitin-protein ligase RBX1 [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed ] | Homo sapiens |