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Browse result for Down-regulation in Hydroxylation

※ introduction

    Protein hydroxylation is a post-translational modification catalyzed by 2-oxoglutarate-dependent dioxygenases. The hydroxylation modification can take place on various amino acids, including but not limited to proline, lysine, asparagine, aspartate and histidine.

Reference
Pubmed: Zurlo G, Guo J, Takada M, Wei W, Zhang Q. New Insights into Protein Hydroxylation and Its Important Role in Human Diseases. Biochim Biophys Acta. 2016 Dec;1866(2):208-220. doi: 10.1016/j.bbcan.2016.09.004.



PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD00011Q166653091
HIF1A
Hypoxia-inducible factor 1-alpha
Homo sapiens
PTMD00022P4693710413
YAP1
Transcriptional coactivator YAP1
Homo sapiens
PTMD00068P423452475
MTOR
Serine/threonine-protein kinase mTOR
Homo sapiens
PTMD00394Q144578678
BECN1
Beclin-1 [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Homo sapiens
PTMD00647Q029625076
PAX2
Paired box protein Pax-2
Homo sapiens
PTMD00863P024521277
COL1A1
Collagen alpha-1 chain
Homo sapiens
PTMD00614P5248018746
Pkm
Pyruvate kinase PKM
Mus musculus