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Browse result for Down-regulation in GPI-anchor

※ introduction

    Glycosylphosphatidylinositol or glycophosphatidylinositol (GPI) is a phosphoglyceride that can be attached to the C-terminus of a protein during posttranslational modification. The resulting GPI-anchored proteins play key roles in a wide variety of biological processes. GPI is composed of a phosphatidylinositol group linked through a carbohydrate-containing linker (glucosamine and mannose glycosidically bound to the inositol residue) and via an ethanolamine phosphate (EtNP) bridge to the C-terminal amino acid of a mature protein. The two fatty acids within the hydrophobic phosphatidyl-inositol group anchor the protein to the cell membrane.

Reference
Wiki: GPI-anchor



PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD00977P010337076
TIMP1
Metalloproteinase inhibitor 1
Homo sapiens
PTMD01382P13987966
CD59
CD59 glycoprotein
Homo sapiens
PTMD01383O750152215
FCGR3B
Low affinity immunoglobulin gamma Fc region receptor III-B
Homo sapiens