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Browse result for Down-regulation in GPI-anchor
※ introduction Glycosylphosphatidylinositol or glycophosphatidylinositol (GPI) is a phosphoglyceride that can be attached to the C-terminus of a protein during posttranslational modification. The resulting GPI-anchored proteins play key roles in a wide variety of biological processes. GPI is composed of a phosphatidylinositol group linked through a carbohydrate-containing linker (glucosamine and mannose glycosidically bound to the inositol residue) and via an ethanolamine phosphate (EtNP) bridge to the C-terminal amino acid of a mature protein. The two fatty acids within the hydrophobic phosphatidyl-inositol group anchor the protein to the cell membrane.
Reference
Wiki: GPI-anchor
Reference
Wiki: GPI-anchor
| PTMD ID | UniProt Accession | Entrez ID | Gene Name | Protein Name | Organism |
|---|---|---|---|---|---|
| PTMD00977 | P01033 | 7076 | TIMP1 | Metalloproteinase inhibitor 1 | Homo sapiens |
| PTMD01382 | P13987 | 966 | CD59 | CD59 glycoprotein | Homo sapiens |
| PTMD01383 | O75015 | 2215 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | Homo sapiens |
