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Browse result for Wilms tumor

※ introduction

    Wilms' tumor or Wilms tumor, also known as nephroblastoma, is a cancer of the kidneys that typically occurs in children (rarely in adults), and occurs most commonly as a renal tumor in child patients. It is named after Max Wilms, the German surgeon (1867¨C1918) who first described it. Approximately 650 cases are diagnosed in the U.S. annually. The majority of cases occur in children with no associated genetic syndromes; however, a minority of children with Wilms' tumor have a congenital abnormality. It is highly responsive to treatment, with about 90 percent of children being cured.

Reference
Wiki: Wilms tumor



PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD00553P195447490
WT1
Wilms tumor protein
Homo sapiens
PTMD00007P352221499
CTNNB1
Catenin beta-1
Homo sapiens
PTMD05326P4971110664
CTCF
Transcriptional repressor CTCF
Homo sapiens
PTMD05443P516542719
GPC3
Glypican-3 [Cleaved into: Glypican-3 alpha subunit; Glypican-3 beta subunit]
Homo sapiens
PTMD06461Q131275978
REST
RE1-silencing transcription factor
Homo sapiens