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Browse result for Ventricular fibrillation

※ introduction

    Ventricular fibrillation (V-fib or VF) is an abnormal heart rhythm in which the ventricles of the heart quiver. It is due to disorganized electrical activity. Ventricular fibrillation results in cardiac arrest with loss of consciousness and no pulse. This is followed by sudden cardiac death in the absence of treatment. Ventricular fibrillation is initially found in about 10% of people with cardiac arrest. Ventricular fibrillation can occur due to coronary heart disease, valvular heart disease, cardiomyopathy, Brugada syndrome, long QT syndrome, electric shock, or intracranial hemorrhage. Diagnosis is by an electrocardiogram (ECG) showing irregular unformed QRS complexes without any clear P waves. An important differential diagnosis is torsades de pointes. Treatment is with cardiopulmonary resuscitation (CPR) and defibrillation. Biphasic defibrillation may be better than monophasic. The medication epinephrine or amiodarone may be given if initial treatments are not effective. Rates of survival among those who are out of hospital when the arrhythmia is detected is about 17% while in hospital it is about 46%.

Reference
Wiki: Ventricular fibrillation



PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD00500P025454000
LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C ]
Homo sapiens
PTMD01525P159241832
DSP
Desmoplakin
Homo sapiens
PTMD01357P6101664672
Pln
Cardiac phospholamban
Rattus norvegicus