※ PTMD 2.0 database Online Browse Options
Browse result for Type 2 diabetes
※ introduction Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.[6] Common symptoms include increased thirst, frequent urination, fatigue and unexplained weight loss.[3] Symptoms may also include increased hunger, having a sensation of pins and needles, and sores (wounds) that do not heal.[3] Often symptoms come on slowly.[6] Long-term complications from high blood sugar include heart disease, stroke, diabetic retinopathy which can result in blindness, kidney failure, and poor blood flow in the limbs which may lead to amputations.[1] The sudden onset of hyperosmolar hyperglycemic state may occur; however, ketoacidosis is uncommon.[4][5]
Reference
Wiki: Type 2 diabetes
Reference
Wiki: Type 2 diabetes
| PTMD ID | UniProt Accession | Entrez ID | Gene Name | Protein Name | Organism |
|---|---|---|---|---|---|
| PTMD00585 | P35558 | 5105 | PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | Homo sapiens |
| PTMD00307 | A0A0U1RQF0 | FASN | Fatty acid synthase | Homo sapiens | |
| PTMD00224 | P62805 | 12150 | H4C1 | Histone H4 | Homo sapiens |
| PTMD00338 | P10636 | 4137 | MAPT | Microtubule-associated protein tau | Homo sapiens |
| PTMD00980 | P02818 | 632 | BGLAP | Osteocalcin | Homo sapiens |
| PTMD00023 | P03372 | 2099 | ESR1 | Estrogen receptor | Homo sapiens |
| PTMD00049 | P31749 | 207 | AKT1 | RAC-alpha serine/threonine-protein kinase | Homo sapiens |
| PTMD00589 | P37231 | 5468 | PPARG | Peroxisome proliferator-activated receptor gamma | Homo sapiens |
| PTMD00598 | P45983 | 5599 | MAPK8 | Mitogen-activated protein kinase 8 | Homo sapiens |
| PTMD00225 | P68431 | 83508 | H3C1 | Histone H3.1 | Homo sapiens |
| PTMD01089 | P35398 | 6095 | RORA | Nuclear receptor ROR-alpha | Homo sapiens |
| PTMD01614 | P37198 | 23636 | NUP62 | Nuclear pore glycoprotein p62 | Homo sapiens |
| PTMD01851 | Q92830 | 2648 | KAT2A | Histone acetyltransferase KAT2A | Homo sapiens |
| PTMD01866 | Q96RI1 | 9971 | NR1H4 | Bile acid receptor | Homo sapiens |
| PTMD01867 | Q96RS0 | 96764 | TGS1 | Trimethylguanosine synthase | Homo sapiens |
| PTMD00854 | Q8CF90 | 37843 | Mafa | Transcription factor MafA | Mus musculus |
| PTMD00919 | Q09137 | 78975 | Prkaa2 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Rattus norvegicus |
| PTMD01399 | E0CZ16 | Klhl3 | Kelch-like protein 3 | Mus musculus | |
| PTMD01401 | G3V7R4 | 84482 | Foxo1 | Forkhead box protein O1 | Rattus norvegicus |
| PTMD01502 | P10361 | 24842 | Tp53 | Cellular tumor antigen p53 | Rattus norvegicus |
| PTMD01555 | P23693 | 29248 | Tnni3 | Troponin I, cardiac muscle | Rattus norvegicus |
| PTMD01557 | P24062 | 25718 | Igf1r | Insulin-like growth factor 1 receptor [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] | Rattus norvegicus |
| PTMD01632 | P47196 | 24185 | Akt1 | RAC-alpha serine/threonine-protein kinase | Rattus norvegicus |
| PTMD01357 | P61016 | 64672 | Pln | Cardiac phospholamban | Rattus norvegicus |
| PTMD01698 | P70313 | 18127 | Nos3 | Nitric oxide synthase 3 | Mus musculus |
| PTMD01715 | Q01147 | 12912 | Creb1 | Cyclic AMP-responsive element-binding protein 1 | Mus musculus |
| PTMD01836 | Q8K1M6 | 74006 | Dnm1l | Dynamin-1-like protein | Mus musculus |
