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Browse result for Polymicrogyria

※ introduction

    Polymicrogyria (PMG) is a condition that affects the development of the human brain by multiple small gyri (microgyri) creating excessive folding of the brain leading to an abnormally thick cortex. This abnormality can affect either one region of the brain or multiple regions. The time of onset has yet to be identified; however, it has been found to occur before birth in either the earlier or later stages of brain development. Early stages include impaired proliferation and migration of neuroblasts, while later stages show disordered post-migration development. The symptoms experienced differ depending on what part of the brain is affected. There is no specific treatment to get rid of this condition, but there are medications that can control the symptoms such as seizures, delayed development or weakened muscles as some of the noted effects.

Reference
Wiki: Polymicrogyria



PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD10738Q925629896
FIG4
Polyphosphoinositide phosphatase
Homo sapiens
PTMD12185Q9BVA134773
TUBB2B
Tubulin beta-2B chain
Homo sapiens
PTMD15017Q9Y6539289
ADGRG1
Adhesion G-protein coupled receptor G1 [Cleaved into: ADGRG1 N-terminal fragment ) ; ADGRG1 C-terminal fragment ) ]
Homo sapiens