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Browse result for Pheochromocytoma
※ introduction Pheochromocytoma is a rare tumor of the adrenal medulla composed of chromaffin cells, also known as pheochromocytes. When a tumor composed of the same cells as a pheochromocytoma develops outside the adrenal gland, it is referred to as a paraganglioma. These neuroendocrine tumors typically release massive amounts of catecholamines which result in the most common symptoms, including hypertension (high blood pressure), tachycardia (fast heart rate), and sweating. Rarely, some tumors (especially paragangliomas) may secrete little to no catecholamines, making diagnosis difficult. While tumors of the head and neck are parasympathetic, their sympathetic counterparts are predominantly located in the abdomen and pelvis, particularly concentrated at the organ of Zuckerkandl.
Reference
Wiki: Pheochromocytoma
Reference
Wiki: Pheochromocytoma
| PTMD ID | UniProt Accession | Entrez ID | Gene Name | Protein Name | Organism |
|---|---|---|---|---|---|
| PTMD00989 | P36957 | 1743 | DLST | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | Homo sapiens |
| PTMD00415 | P40337 | 7428 | VHL | von Hippel-Lindau disease tumor suppressor | Homo sapiens |
| PTMD00625 | P61244 | 4149 | MAX | Protein max | Homo sapiens |
| PTMD00230 | P37840 | 6622 | SNCA | Alpha-synuclein | Homo sapiens |
| PTMD00368 | P07949 | 5979 | RET | Proto-oncogene tyrosine-protein kinase receptor Ret [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] | Homo sapiens |
| PTMD04492 | P21912 | 6390 | SDHB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | Homo sapiens |
