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Browse result for Pheochromocytoma

※ introduction

    Pheochromocytoma is a rare tumor of the adrenal medulla composed of chromaffin cells, also known as pheochromocytes. When a tumor composed of the same cells as a pheochromocytoma develops outside the adrenal gland, it is referred to as a paraganglioma. These neuroendocrine tumors typically release massive amounts of catecholamines which result in the most common symptoms, including hypertension (high blood pressure), tachycardia (fast heart rate), and sweating. Rarely, some tumors (especially paragangliomas) may secrete little to no catecholamines, making diagnosis difficult. While tumors of the head and neck are parasympathetic, their sympathetic counterparts are predominantly located in the abdomen and pelvis, particularly concentrated at the organ of Zuckerkandl.

Reference
Wiki: Pheochromocytoma



PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD00989P369571743
DLST
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
Homo sapiens
PTMD00415P403377428
VHL
von Hippel-Lindau disease tumor suppressor
Homo sapiens
PTMD00625P612444149
MAX
Protein max
Homo sapiens
PTMD00230P378406622
SNCA
Alpha-synuclein
Homo sapiens
PTMD00368P079495979
RET
Proto-oncogene tyrosine-protein kinase receptor Ret [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Homo sapiens
PTMD04492P219126390
SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Homo sapiens