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Browse result for Non-small cell lung cancer

※ introduction

    Non-small-cell lung cancer (NSCLC), or non-small-cell lung carcinoma, is any type of epithelial lung cancer other than small-cell lung cancer (SCLC). NSCLC accounts for about 85% of all lung cancers.[1][2][3] As a class, NSCLCs are relatively insensitive to chemotherapy, compared to small-cell carcinoma. When possible, they are primarily treated by surgical resection with curative intent, although chemotherapy has been used increasingly both preoperatively (neoadjuvant chemotherapy) and postoperatively (adjuvant chemotherapy).

Reference
Wiki: Non-small cell lung cancer


PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD00498P011163845
KRAS
GTPase KRas [Cleaved into: GTPase KRas, N-terminally processed]
Homo sapiens
PTMD00097Q141459817
KEAP1
Kelch-like ECH-associated protein 1
Homo sapiens
PTMD00177Q969H055294
FBXW7
F-box/WD repeat-containing protein 7
Homo sapiens
PTMD00081P404245087
PBX1
Pre-B-cell leukemia transcription factor 1
Homo sapiens
PTMD00020P604845728
PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Homo sapiens
PTMD00021P129316714
SRC
Proto-oncogene tyrosine-protein kinase Src
Homo sapiens
PTMD00096Q9UM474854
NOTCH3
Neurogenic locus notch homolog protein 3 [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]
Homo sapiens
PTMD00004O153573636
INPPL1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
Homo sapiens
PTMD00123Q0966679026
AHNAK
Neuroblast differentiation-associated protein AHNAK
Homo sapiens
PTMD00129Q131588772
FADD
FAS-associated death domain protein
Homo sapiens
PTMD00367P612546154
RPL26
Large ribosomal subunit protein uL24
Homo sapiens
PTMD00381Q8NB1619725
MLKL
Mixed lineage kinase domain-like protein
Homo sapiens
PTMD00179P465314851
NOTCH1
Neurogenic locus notch homolog protein 1 [Cleaved into: Notch 1 extracellular truncation ; Notch 1 intracellular domain ]
Homo sapiens
PTMD00176P339817272
TTK
Dual specificity protein kinase TTK
Homo sapiens
PTMD00064Q142472017
CTTN
Src substrate cortactin
Homo sapiens
PTMD00172P150902167
FABP4
Fatty acid-binding protein, adipocyte
Homo sapiens
PTMD00040P407636774
STAT3
Signal transducer and activator of transcription 3
Homo sapiens
PTMD00318Q9BWF35936
RBM4
RNA-binding protein 4
Homo sapiens
PTMD00322P254907528
YY1
Transcriptional repressor protein YY1
Homo sapiens
PTMD00189P086707431
VIM
Vimentin
Homo sapiens
PTMD00255P086483678
ITGA5
Integrin alpha-5 [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain]
Homo sapiens
PTMD00067P005331956
EGFR
Epidermal growth factor receptor
Homo sapiens
PTMD00071P179363486
IGFBP3
Insulin-like growth factor-binding protein 3
Homo sapiens
PTMD00007P352221499
CTNNB1
Catenin beta-1
Homo sapiens
PTMD00267P490235829
PXN
Paxillin
Homo sapiens
PTMD00287O14867571
BACH1
Transcription regulator protein BACH1
Homo sapiens
PTMD00332P080693480
IGF1R
Insulin-like growth factor 1 receptor [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Homo sapiens
PTMD00082P24385595
CCND1
G1/S-specific cyclin-D1
Homo sapiens
PTMD00276Q9NZQ729126
CD274
Programmed cell death 1 ligand 1
Homo sapiens
PTMD00037Q156727291
TWIST1
Twist-related protein 1
Homo sapiens
PTMD00363P313506241
RRM2
Ribonucleoside-diphosphate reductase subunit M2
Homo sapiens
PTMD00018Q166447867
MAPKAPK3
MAP kinase-activated protein kinase 3
Homo sapiens
PTMD00073P546195571
PRKAG1
5'-AMP-activated protein kinase subunit gamma-1
Homo sapiens
PTMD00027P011064609
MYC
Myc proto-oncogene protein
Homo sapiens
PTMD00383Q8N7H554623
PAF1
RNA polymerase II-associated factor 1 homolog
Homo sapiens
PTMD00146Q998356608
SMO
Protein smoothened
Homo sapiens
PTMD00126P005585230
PGK1
Phosphoglycerate kinase 1
Homo sapiens
PTMD00105O434749314
KLF4
Krueppel-like factor 4
Homo sapiens
PTMD00187P012293972
LHB
Lutropin subunit beta
Homo sapiens
PTMD00006P046377157
TP53
Cellular tumor antigen p53
Homo sapiens
PTMD00320O147379141
PDCD5
Programmed cell death protein 5
Homo sapiens
PTMD00058P273615595
MAPK3
Mitogen-activated protein kinase 3
Homo sapiens
PTMD00066O435242309
FOXO3
Forkhead box protein O3
Homo sapiens
PTMD00466O435838562
DENR
Density-regulated protein
Homo sapiens
PTMD00133O951409927
MFN2
Mitofusin-2
Homo sapiens
PTMD00495P003383939
LDHA
L-lactate dehydrogenase A chain
Homo sapiens
PTMD00168P054123725
JUN
Transcription factor Jun
Homo sapiens
PTMD00202P085814233
MET
Hepatocyte growth factor receptor
Homo sapiens
PTMD00518P085904634
MYL3
Myosin light chain 3
Homo sapiens
PTMD00219P146185315
PKM
Pyruvate kinase PKM
Homo sapiens
PTMD00048P153117430
EZR
Ezrin
Homo sapiens
PTMD00544P174807343
UBTF
Nucleolar transcription factor 1
Homo sapiens
PTMD00563P239216240
RRM1
Ribonucleoside-diphosphate reductase large subunit
Homo sapiens
PTMD00049P31749207
AKT1
RAC-alpha serine/threonine-protein kinase
Homo sapiens
PTMD00229P35613682
BSG
Basigin
Homo sapiens
PTMD00041P498412932
GSK3B
Glycogen synthase kinase-3 beta
Homo sapiens
PTMD00623P601747167
TPI1
Triosephosphate isomerase
Homo sapiens
PTMD00225P6843183508
H3C1
Histone H3.1
Homo sapiens
PTMD00160Q042065970
RELA
Transcription factor p65
Homo sapiens
PTMD00210Q053975747
PTK2
Focal adhesion kinase 1
Homo sapiens
PTMD00331Q078204170
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1
Homo sapiens
PTMD00677Q1350910381
TUBB3
Tubulin beta-3 chain
Homo sapiens
PTMD00694Q151165133
PDCD1
Programmed cell death protein 1
Homo sapiens
PTMD00743Q8N6T751548
SIRT6
NAD-dependent protein deacylase sirtuin-6
Homo sapiens
PTMD00763Q929458570
KHSRP
Far upstream element-binding protein 2
Homo sapiens
PTMD00772Q96KB555872
PBK
Lymphokine-activated killer T-cell-originated protein kinase
Homo sapiens
PTMD00814Q9NZI529841
GRHL1
Grainyhead-like protein 1 homolog
Homo sapiens
PTMD00817Q9UD7184152
PPP1R1B
Protein phosphatase 1 regulatory subunit 1B
Homo sapiens
PTMD00288P372756935
ZEB1
Zinc finger E-box-binding homeobox 1
Homo sapiens
PTMD00068P423452475
MTOR
Serine/threonine-protein kinase mTOR
Homo sapiens
PTMD00619P533505347
PLK1
Serine/threonine-protein kinase PLK1
Homo sapiens
PTMD00407Q166595597
MAPK6
Mitogen-activated protein kinase 6
Homo sapiens
PTMD00393P094672203
FBP1
Fructose-1,6-bisphosphatase 1
Homo sapiens
PTMD00301P193384691
NCL
Nucleolin
Homo sapiens
PTMD00585P355585105
PCK1
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
Homo sapiens
PTMD00201P627536194
RPS6
Small ribosomal subunit protein eS6
Homo sapiens
PTMD00224P6280512150
H4C1
Histone H4
Homo sapiens
PTMD00216Q1308531
ACACA
Acetyl-CoA carboxylase 1
Homo sapiens
PTMD00204Q131535058
PAK1
Serine/threonine-protein kinase PAK 1
Homo sapiens
PTMD01295Q153032066
ERBB4
Receptor tyrosine-protein kinase erbB-4 [Cleaved into: ERBB4 intracellular domain ]
Homo sapiens
PTMD01132Q1495610457
GPNMB
Transmembrane glycoprotein NMB
Homo sapiens
PTMD01167Q96H1591937
TIMD4
T-cell immunoglobulin and mucin domain-containing protein 4
Homo sapiens
PTMD01172Q9BXY884707
BEX2
Protein BEX2
Homo sapiens
PTMD01418O155033638
INSIG1
Insulin-induced gene 1 protein
Homo sapiens
PTMD01451O949252744
GLS
Glutaminase kidney isoform, mitochondrial [Cleaved into: Glutaminase kidney isoform, mitochondrial 68 kDa chain; Glutaminase kidney isoform, mitochondrial 65 kDa chain]
Homo sapiens
PTMD01278P27695328
APEX1
DNA repair nuclease/redox regulator APEX1 endonuclease) [Cleaved into: DNA repair nuclease/redox regulator APEX1, mitochondrial]
Homo sapiens
PTMD01611P357901119
CHKA
Choline kinase alpha
Homo sapiens
PTMD01723Q048281645
AKR1C1
Aldo-keto reductase family 1 member C1
Homo sapiens
PTMD01737Q129591739
DLG1
Disks large homolog 1
Homo sapiens
PTMD01902Q9NPB650855
PARD6A
Partitioning defective 6 homolog alpha
Homo sapiens
PTMD01904Q9NR1955902
ACSS2
Acetyl-coenzyme A synthetase, cytoplasmic
Homo sapiens
PTMD01950Q9Y5U451141
INSIG2
Insulin-induced gene 2 protein
Homo sapiens
PTMD03346O9507151366
UBR5
E3 ubiquitin-protein ligase UBR5
Homo sapiens
PTMD04470P213594763
NF1
Neurofibromin [Cleaved into: Neurofibromin truncated]
Homo sapiens
PTMD04926P35414187
APLNR
Apelin receptor
Homo sapiens
PTMD05942P7833210180
RBM6
RNA-binding protein 6
Homo sapiens
PTMD10877Q9301524142
NAA80
N-alpha-acetyltransferase 80
Homo sapiens
PTMD00580P3175011651
Akt1
RAC-alpha serine/threonine-protein kinase
Mus musculus