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Browse result for Left ventricular noncompaction

※ introduction

    Noncompaction cardiomyopathy (NCC) is a rare congenital disease of heart muscle that affects both children and adults. It results from abnormal prenatal development of heart muscle. During development, the majority of the heart muscle is a sponge-like meshwork of interwoven myocardial fibers. As normal development progresses, these trabeculated structures undergo significant compaction that transforms them from spongy to solid. This process is particularly apparent in the ventricles, and particularly so in the left ventricle. Noncompaction cardiomyopathy results when there is failure of this process of compaction. Because the consequence of non-compaction is particularly evident in the left ventricle, the condition is also called left ventricular noncompaction. Other hypotheses and models have been proposed, none of which is as widely accepted as the noncompaction model. Symptoms range greatly in severity. Most are a result of a poor pumping performance by the heart. The disease can be associated with other problems with the heart and the body.

Reference
Wiki: Left ventricular noncompaction



PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD01064P094937168
TPM1
Tropomyosin alpha-1 chain
Homo sapiens
PTMD01525P159241832
DSP
Desmoplakin
Homo sapiens
PTMD01694P6803270
ACTC1
Actin, alpha cardiac muscle 1 [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Homo sapiens
PTMD01751Q145246331
SCN5A
Sodium channel protein type 5 subunit alpha
Homo sapiens
PTMD01131Q148964607
MYBPC3
Myosin-binding protein C, cardiac-type
Homo sapiens
PTMD01878Q9BR3957158
JPH2
Junctophilin-2 [Cleaved into: Junctophilin-2 N-terminal fragment ]
Homo sapiens
PTMD04130P128834625
MYH7
Myosin-7
Homo sapiens
PTMD06704Q141922274
FHL2
Four and a half LIM domains protein 2
Homo sapiens
PTMD13046Q9HAZ263976
PRDM16
Histone-lysine N-methyltransferase PRDM16
Homo sapiens
PTMD14855Q9Y4J81837
DTNA
Dystrobrevin alpha
Homo sapiens