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Browse result for Laryngeal cancer

※ introduction

    Laryngeal cancer or throat cancer is a kind of cancer that can develop in any part of the larynx. It is typically a squamous-cell carcinoma, reflecting its origin from the epithelium of the larynx. The prognosis is affected by the location of the tumour. For the purposes of staging, the larynx is divided into three anatomical regions: the glottis (true vocal cords, anterior and posterior commissures); the supraglottis (epiglottis, arytenoids and aryepiglottic folds, and false cords); and the subglottis. Most laryngeal cancers originate in the glottis, with supraglottic and subglottic tumours being less frequent. Laryngeal cancer may spread by: direct extension to adjacent structures, metastasis to regional cervical lymph nodes, or via the blood stream. The most common site of distant metastases is the lung. Laryngeal cancer occurred in 177,000 people in 2018, and resulted in 94,800 deaths (an increase from 76,000 deaths in 1990). Five-year survival rates in the United States are 60.3%.

Reference
Wiki: Laryngeal cancer



PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD00024O149656790
AURKA
Aurora kinase A
Homo sapiens
PTMD00049P31749207
AKT1
RAC-alpha serine/threonine-protein kinase
Homo sapiens
PTMD00040P407636774
STAT3
Signal transducer and activator of transcription 3
Homo sapiens
PTMD00225P6843183508
H3C1
Histone H3.1
Homo sapiens