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Browse result for Hereditary pancreatitis
※ introduction Hereditary pancreatitis (HP) is an inflammation of the pancreas due to genetic causes. It was first described in 1952 by Comfort and Steinberg but it was not until 1996 that Whitcomb et al isolated the first responsible mutation in the trypsinogen gene (PRSS1) on the long arm of chromosome seven (7q35).
The term "hereditary pancreatitis" is used when a genetic biomarker is identified, and "familial pancreatitis" otherwise.
Reference
Wiki: Hereditary pancreatitis
Reference
Wiki: Hereditary pancreatitis
| PTMD ID | UniProt Accession | Entrez ID | Gene Name | Protein Name | Organism |
|---|---|---|---|---|---|
| PTMD03608 | P00995 | 6690 | SPINK1 | Serine protease inhibitor Kazal-type 1 | Homo sapiens |
| PTMD03836 | P07477 | 5644 | PRSS1 | Serine protease 1 [Cleaved into: Alpha-trypsin chain 1; Alpha-trypsin chain 2] | Homo sapiens |
