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Browse result for Familial hemophagocytic lymphohistiocytosis

※ introduction

    In hematology, hemophagocytic lymphohistiocytosis (HLH), also known as haemophagocytic lymphohistiocytosis (British spelling), and hemophagocytic or haemophagocytic syndrome, is an uncommon hematologic disorder seen more often in children than in adults. It is a life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation of benign lymphocytes and macrophages that secrete high amounts of inflammatory cytokines. It is classified as one of the cytokine storm syndromes. There are inherited and non-inherited (acquired) causes of HLH.

Reference
Wiki: Familial hemophagocytic lymphohistiocytosis



PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD01519P142225551
PRF1
Perforin-1
Homo sapiens
PTMD07041Q158336813
STXBP2
Syntaxin-binding protein 2
Homo sapiens
PTMD08642Q70J9920129
UNC13D
Protein unc-13 homolog D
Homo sapiens