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Browse result for Chilblain lupus
※ introduction Chilblain lupus erythematosus was initially described by Hutchinson in 1888 as an uncommon manifestation of chronic cutaneous lupus erythematosus. Chilblain lupus erythematosus is characterized by a rash that primarily affects acral surfaces that are frequently exposed to cold temperatures, such as the toes, fingers, ears, and nose. The rash is defined by oedematous skin, nodules, and tender plaques with a purple discoloration.
Its pathogenetic factors include cold-induced vascular thrombosis, blood stasis, and impaired microcirculation. Chilblain lupus has been linked to anti-Ro antibodies.
Reference
Wiki: Chilblain lupus
Reference
Wiki: Chilblain lupus
| PTMD ID | UniProt Accession | Entrez ID | Gene Name | Protein Name | Organism |
|---|---|---|---|---|---|
| PTMD14815 | Q9Y3Z3 | 25939 | SAMHD1 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | Homo sapiens |
