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Browse result for Atrioventricular septal defect
※ introduction Atrioventricular septal defect (AVSD) or atrioventricular canal defect (AVCD), also known as "common atrioventricular canal" or "endocardial cushion defect" (ECD), is characterized by a deficiency of the atrioventricular septum of the heart that creates connections between all four of its chambers. It is a very specific combination of 3 defects:
1) Atrial Septal Defect (ASD), a hole in the wall between the right and left atria;
2) Ventricular Septal Defect (VSD), a hole in the wall between the right and left ventricles; and
3) Abnormalities of the mitral and/or tricuspid valves.
AVCD is caused by an abnormal or inadequate fusion of the superior and inferior endocardial cushions with the mid portion of the atrial septum and the muscular portion of the ventricular septum. Unlike some heart defects, the condition will not resolve over time and most infants must undergo open heart surgery. The surgery to correct this defect is usually successful and most babies do very well post-op.
Reference
Wiki: Atrioventricular septal defect
Reference
Wiki: Atrioventricular septal defect
| PTMD ID | UniProt Accession | Entrez ID | Gene Name | Protein Name | Organism |
|---|---|---|---|---|---|
| PTMD00908 | P43694 | 2626 | GATA4 | Transcription factor GATA-4 | Homo sapiens |
| PTMD10848 | Q92908 | 2627 | GATA6 | Transcription factor GATA-6 | Homo sapiens |
| PTMD11307 | Q96HD1 | 78987 | CRELD1 | Protein disulfide isomerase CRELD1 | Homo sapiens |
