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Browse result for Ameloblastoma

※ introduction

    Ameloblastoma is a rare, benign or cancerous tumor of odontogenic epithelium (ameloblasts, or outside portion, of the teeth during development) much more commonly appearing in the lower jaw than the upper jaw. It was recognized in 1827 by Cusack. This type of odontogenic neoplasm was designated as an adamantinoma in 1885 by the French physician Louis-Charles Malassez. It was finally renamed to the modern name ameloblastoma in 1930 by Ivey and Churchill. While these tumors are rarely malignant or metastatic (that is, they rarely spread to other parts of the body), and progress slowly, the resulting lesions can cause severe abnormalities of the face and jaw leading to severe disfiguration. Additionally, as abnormal cell growth easily infiltrates and destroys surrounding bony tissues, wide surgical excision is required to treat this disorder. If an aggressive tumor is left untreated, it can obstruct the nasal and oral airways making it impossible to breathe without oropharyngeal intervention. The term "ameloblastoma" is from the early English word amel, meaning enamel and the Greek word blastos, meaning germ.

Reference
Wiki: Ameloblastoma



PTMD IDUniProt AccessionEntrez IDGene NameProtein NameOrganism
PTMD00057Q9NYJ823118
TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
Homo sapiens
PTMD00634P683667277
TUBA4A
Tubulin alpha-4A chain
Homo sapiens
PTMD00259Q135411978
EIF4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1
Homo sapiens
PTMD00068P423452475
MTOR
Serine/threonine-protein kinase mTOR
Homo sapiens
PTMD00943P234436198
RPS6KB1
Ribosomal protein S6 kinase beta-1
Homo sapiens