Uniprot AC Entrez ID Gene Name Disease Cell Type PTM Type State Position PMID P28562 1843 DUSP1 CL100 MKP1 PTPN10 VH1 Cervical squamous cell carcinoma and endocervical adenocarcinoma Ubiquitination N K122 P28562 1843 DUSP1 CL100 MKP1 PTPN10 VH1 Bladder urothelial carcinoma Ubiquitination N K221 P28562 1843 DUSP1 CL100 MKP1 PTPN10 VH1 Skin cutaneous melanoma Phosphorylation N S323 P28562 1843 DUSP1 CL100 MKP1 PTPN10 VH1 Stomach adenocarcinoma Phosphorylation N S323 P28562 1843 DUSP1 CL100 MKP1 PTPN10 VH1 Brain lower grade glioma Phosphorylation N S359 P28562 1843 DUSP1 CL100 MKP1 PTPN10 VH1 Uterus adenocarcinoma Phosphorylation N S359 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Skin cutaneous melanoma Phosphorylation N S31 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Skin cutaneous melanoma Ubiquitination N K32 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Bladder urothelial carcinoma Phosphorylation N T63 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Bladder urothelial carcinoma Phosphorylation N Y66 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Bladder urothelial carcinoma Ubiquitination N K71 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Lung squamous cell carcinoma SUMOylation N K185 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Lung squamous cell carcinoma Ubiquitination N K185 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Breast adenocarcinoma Ubiquitination N K289 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Breast adenocarcinoma Ubiquitination N K297 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Thyroid carcinoma Acetylation N K389 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Thyroid carcinoma Ubiquitination N K389 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Thyroid carcinoma Methylation N K391 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Thyroid carcinoma SUMOylation N K391 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Thyroid carcinoma Ubiquitination N K391 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Lung adenocarcinoma Phosphorylation N S451 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Lung adenocarcinoma Phosphorylation N T455 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Lung adenocarcinoma Phosphorylation N T458 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Lung adenocarcinoma Ubiquitination N K460 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Uterine carcinosarcoma Acetylation N K532 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Uterine carcinosarcoma Ubiquitination N K532 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Cervical cancer Hydroxylation N P564 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Head and neck squamous cell carcinoma Phosphorylation N S589 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Breast invasive carcinoma Ubiquitination N K636 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Hepatocellular carcinoma Ubiquitination N K636 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Breast invasive carcinoma Phosphorylation N S641 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Hepatocellular carcinoma Phosphorylation N S641 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Breast invasive carcinoma Phosphorylation N S643 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Breast invasive carcinoma Ubiquitination N K649 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Cervical squamous cell carcinoma and endocervical adenocarcinoma Ubiquitination N K682 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Cervical squamous cell carcinoma and endocervical adenocarcinoma Phosphorylation N S683 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Stomach adenocarcinoma Phosphorylation N S683 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Cervical squamous cell carcinoma and endocervical adenocarcinoma Phosphorylation N S687 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Stomach adenocarcinoma Phosphorylation N S687 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Stomach adenocarcinoma Phosphorylation N S692 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Bladder urothelial carcinoma Phosphorylation N S696 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Stomach adenocarcinoma Phosphorylation N S696 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Bladder urothelial carcinoma Phosphorylation N T700 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Bladder urothelial carcinoma Acetylation N K709 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Bladder urothelial carcinoma Ubiquitination N K709 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Uterine corpus endometrial carcinoma Ubiquitination N K721 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Uterine corpus endometrial carcinoma Phosphorylation N S727 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Stomach adenocarcinoma Phosphorylation N T796 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Blastoma Hydroxylation N N803 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Pancreatic cancer Hydroxylation N N803 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Breast invasive carcinoma Phosphorylation N S809 Q96EB6 23411 SIRT1 SIR2L1 Thyroid carcinoma Phosphorylation N S14 Q96EB6 23411 SIRT1 SIR2L1 Skin cancer Phosphorylation N S27 Q96EB6 23411 SIRT1 SIR2L1 Stomach cancer Phosphorylation N S27 Q96EB6 23411 SIRT1 SIR2L1 Transitional cell carcinoma Phosphorylation N S47 Q96EB6 23411 SIRT1 SIR2L1 Bladder urothelial carcinoma Phosphorylation N S159 Q96EB6 23411 SIRT1 SIR2L1 Urinary bladder cancer Phosphorylation N S159 Q96EB6 23411 SIRT1 SIR2L1 Bladder urothelial carcinoma Phosphorylation N S162 Q96EB6 23411 SIRT1 SIR2L1 Adrenocortical carcinoma Phosphorylation N Y280 Q96EB6 23411 SIRT1 SIR2L1 Lung adenocarcinoma Phosphorylation N Y301 Q96EB6 23411 SIRT1 SIR2L1 Stomach adenocarcinoma Ubiquitination N K314 Q96EB6 23411 SIRT1 SIR2L1 Stomach adenocarcinoma Ubiquitination N K328 Q96EB6 23411 SIRT1 SIR2L1 Prostate adenocarcinoma Phosphorylation N T344 Q96EB6 23411 SIRT1 SIR2L1 Liver cancer S-Nitrosylation N C395 Q96EB6 23411 SIRT1 SIR2L1 Colorectal cancer S-Nitrosylation N C398 Q96EB6 23411 SIRT1 SIR2L1 Brain lower grade glioma Phosphorylation N Y428 Q96EB6 23411 SIRT1 SIR2L1 Skin cutaneous melanoma Ubiquitination N K499 Q96EB6 23411 SIRT1 SIR2L1 Pancreatic adenocarcinoma Ubiquitination N K506 Q96EB6 23411 SIRT1 SIR2L1 Hepatocellular carcinoma Ubiquitination N K513 Q96EB6 23411 SIRT1 SIR2L1 Pancreatic adenocarcinoma Ubiquitination N K513 Q96EB6 23411 SIRT1 SIR2L1 Lung adenocarcinoma Phosphorylation N T544 Q96EB6 23411 SIRT1 SIR2L1 Lung adenocarcinoma Phosphorylation N S545 Q96EB6 23411 SIRT1 SIR2L1 Head and neck squamous cell carcinoma Phosphorylation N T554 Q96EB6 23411 SIRT1 SIR2L1 Lung adenocarcinoma Phosphorylation N T554 Q96EB6 23411 SIRT1 SIR2L1 Head and neck squamous cell carcinoma Ubiquitination N K561 Q96EB6 23411 SIRT1 SIR2L1 Head and neck squamous cell carcinoma Phosphorylation N S562 Q96EB6 23411 SIRT1 SIR2L1 Bladder urothelial carcinoma Ubiquitination N K610 Q96EB6 23411 SIRT1 SIR2L1 Esophageal adenocarcinoma Ubiquitination N K610 Q96EB6 23411 SIRT1 SIR2L1 Bladder urothelial carcinoma Phosphorylation N S615 Q96EB6 23411 SIRT1 SIR2L1 Breast adenocarcinoma Phosphorylation N S615 Q96EB6 23411 SIRT1 SIR2L1 Breast invasive carcinoma Phosphorylation N S615 Q96EB6 23411 SIRT1 SIR2L1 Esophageal adenocarcinoma Phosphorylation N S615 Q96EB6 23411 SIRT1 SIR2L1 Bladder urothelial carcinoma Phosphorylation N T619 Q96EB6 23411 SIRT1 SIR2L1 Breast adenocarcinoma Phosphorylation N T619 Q96EB6 23411 SIRT1 SIR2L1 Breast invasive carcinoma Phosphorylation N T619 Q96EB6 23411 SIRT1 SIR2L1 Esophageal adenocarcinoma Phosphorylation N T619 Q96EB6 23411 SIRT1 SIR2L1 Bladder urothelial carcinoma Methylation N K622 Q96EB6 23411 SIRT1 SIR2L1 Breast adenocarcinoma Methylation N K622 Q96EB6 23411 SIRT1 SIR2L1 Breast invasive carcinoma Methylation N K622 Q96EB6 23411 SIRT1 SIR2L1 Esophageal adenocarcinoma Methylation N K622 Q96EB6 23411 SIRT1 SIR2L1 Breast invasive carcinoma Phosphorylation N S682 Q96EB6 23411 SIRT1 SIR2L1 Invasive lobular carcinoma Phosphorylation N S682 Q96EB6 23411 SIRT1 SIR2L1 Breast invasive carcinoma Phosphorylation N T719 Q96EB6 23411 SIRT1 SIR2L1 Renal cell carcinoma Phosphorylation N T719 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Cholangiocarcinoma CCA tissues Poly(ADP-ribosyl)ation U 37821935 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Pancreatic cancer pancreatic cancer tissues Deacetylation P 29343850 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Hepatocellular carcinoma tumor tissue Deubiquitination U 31776228 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Hepatocellular carcinoma tumor tissue Deubiquitination U 34420039 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Ischemic myocardium heart tissues Hydroxylation U 34205318 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Clear cell renal cell carcinoma ccRCC tissues Hydroxylation U 34098990 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Neuropathic pain spinal cord tissues Methylation U 38402915 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Triple-negative breast cancer breast cancer tissues Hydroxylation U 30367042 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Colon cancer colon cancer cells Glutathionylation U 29113799 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Renal cell carcinoma tumor tissue Ubiquitination D 36799168 Q96EB6 23411 SIRT1 SIR2L1 Colorectal cancer tumor tissue Ubiquitination A 32361710 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Cancer tumor tissue Ubiquitination D 29121446 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Hepatocellular carcinoma HCC cells Ubiquitination D 32034309 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Colorectal cancer tumor tissue Ubiquitination D 32796813 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Plasma cell neoplasia B-cell neoplasia Hydroxylation D 19737309 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Glioblastoma glioblastoma cells Hydroxylation D 34369622 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Colorectal cancer tumor tissue Arginine methylation U R282 34753906 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Liver cancer MHCC-97L cells DeSUMOylation N K391 28258134 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Cancer tumor tissue Demethylation U K391 28534506 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Ovarian cancer ovarian cancer cells Hydroxylation D P402 31285371 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Cancer tumor tissue Threonine phosphorylation U T455 34211090 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Liver cancer MHCC-97L cells DeSUMOylation N K477 28258134 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Ovarian cancer ovarian cancer cells Hydroxylation D P564 31285371 Q96EB6 23411 SIRT1 SIR2L1 Colon cancer colon cancer cell line Serine phosphorylation U S27 34826187 Q96EB6 23411 SIRT1 SIR2L1 Hepatocellular carcinoma HCC tissues Serine phosphorylation U S47 34188177 Q96EB6 23411 SIRT1 SIR2L1 Colon cancer colon tumor tissues Deacetylation U K610 37530744 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Arterial calcification Deacetylation D 35232219 P28562 1843 DUSP1 CL100 MKP1 PTPN10 VH1 Nonalcoholic steatohepatitis Serine phosphorylation D S428 37669951 Q96EB6 23411 SIRT1 SIR2L1 Atherosclerosis Serine phosphorylation A S27 23754392 Q96EB6 23411 SIRT1 SIR2L1 Atherosclerosis Serine phosphorylation A S47 23754392 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Pulmonary hypertension pulmonary artery smooth muscle cell Hydroxylation D 36564027 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Cancer tumor tissue Neddylation D 33097763 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Cancer tumor tissue Hydroxylation D 28534506 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Prostate cancer PCa tissues Lactylation U 36209908 P28562 1843 DUSP1 CL100 MKP1 PTPN10 VH1 Diabetes blood monocytes Glutathionylation U 27670844 Q96EB6 23411 SIRT1 SIR2L1 Thoracic aortic aneurysm Our novel findings strongly suggest a causal role of Glutathionylation of SirT1 in the pathogenesis of TAA. Glutathionylation U 37288573 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Breast cancer FFPE tissues Hydroxylation U P402 24563687 Q16665 3091 HIF1A BHLHE78 MOP1 PASD8 Breast cancer FFPE tissues Hydroxylation U P564 24563687 P28562 1843 DUSP1 CL100 MKP1 PTPN10 VH1 Major depressive disorder Phosphorylation P 22787484 Q96EB6 23411 SIRT1 SIR2L1 Atherogenesis Sulfhydration D 29343087 Q96EB6 23411 SIRT1 SIR2L1 Diabetic nephropathy Sulfhydration D 33279869 Q96EB6 23411 SIRT1 SIR2L1 Parkinson's disease Ubiquitination U 29571747