Uniprot AC Entrez ID Gene Name Disease Cell Type PTM Type State Position PMID Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N T23 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N S24 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N S25 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cardiofaciocutaneous syndrome Ubiquitination N K36 Q02750 5604 MAP2K1 MEK1 PRKMK1 Colon adenocarcinoma Phosphorylation C T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Skin cutaneous melanoma Phosphorylation C T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cardiofaciocutaneous syndrome Phosphorylation N T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Chronic lymphocytic leukemia Phosphorylation N T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Colon adenocarcinoma Phosphorylation N T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Head and neck squamous cell carcinoma Phosphorylation N T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Lung adenocarcinoma Phosphorylation N T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Melorheostosis Phosphorylation N T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Non-Hodgkin's lymphoma Phosphorylation N T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Pancreatic adenocarcinoma Phosphorylation N T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rectum adenocarcinoma Phosphorylation N T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Skin cutaneous melanoma Phosphorylation N T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Thymoma Phosphorylation N T55 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cardiofaciocutaneous syndrome Ubiquitination N K57 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cardiofaciocutaneous syndrome Ubiquitination N K57 Q02750 5604 MAP2K1 MEK1 PRKMK1 Chronic lymphocytic leukemia Ubiquitination N K57 Q02750 5604 MAP2K1 MEK1 PRKMK1 Colon adenocarcinoma Ubiquitination N K57 Q02750 5604 MAP2K1 MEK1 PRKMK1 Head and neck squamous cell carcinoma Ubiquitination N K57 Q02750 5604 MAP2K1 MEK1 PRKMK1 Lung adenocarcinoma Ubiquitination N K57 Q02750 5604 MAP2K1 MEK1 PRKMK1 Melorheostosis Ubiquitination N K57 Q02750 5604 MAP2K1 MEK1 PRKMK1 Non-Hodgkin's lymphoma Ubiquitination N K57 Q02750 5604 MAP2K1 MEK1 PRKMK1 Pancreatic adenocarcinoma Ubiquitination N K57 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rectum adenocarcinoma Ubiquitination N K57 Q02750 5604 MAP2K1 MEK1 PRKMK1 Skin cutaneous melanoma Ubiquitination N K57 Q02750 5604 MAP2K1 MEK1 PRKMK1 Thymoma Ubiquitination N K57 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cardiofaciocutaneous syndrome Ubiquitination N K64 Q02750 5604 MAP2K1 MEK1 PRKMK1 Head and neck squamous cell carcinoma Ubiquitination N K64 Q02750 5604 MAP2K1 MEK1 PRKMK1 Lung adenocarcinoma Ubiquitination N K64 Q02750 5604 MAP2K1 MEK1 PRKMK1 Non-Hodgkin's lymphoma Ubiquitination N K64 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Ubiquitination N K64 Q02750 5604 MAP2K1 MEK1 PRKMK1 Skin cutaneous melanoma Ubiquitination N K64 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Ubiquitination N K70 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation C S72 Q02750 5604 MAP2K1 MEK1 PRKMK1 Breast invasive carcinoma Ubiquitination N K88 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cardiofaciocutaneous syndrome Ubiquitination N K88 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cardiofaciocutaneous syndrome Ubiquitination N K97 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cervical squamous cell carcinoma and endocervical adenocarcinoma Ubiquitination N K97 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cervical squamous cell carcinoma and endocervical adenocarcinoma SUMOylation N K104 Q02750 5604 MAP2K1 MEK1 PRKMK1 Noonan syndrome SUMOylation N K104 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy SUMOylation N K104 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cervical squamous cell carcinoma and endocervical adenocarcinoma Ubiquitination N K104 Q02750 5604 MAP2K1 MEK1 PRKMK1 Noonan syndrome Ubiquitination N K104 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Ubiquitination N K104 Q02750 5604 MAP2K1 MEK1 PRKMK1 Stomach adenocarcinoma Acetylation N K175 Q02750 5604 MAP2K1 MEK1 PRKMK1 Stomach adenocarcinoma Ubiquitination N K175 Q02750 5604 MAP2K1 MEK1 PRKMK1 Noonan syndrome Ubiquitination N K192 Q02750 5604 MAP2K1 MEK1 PRKMK1 Noonan syndrome Phosphorylation N S194 Q02750 5604 MAP2K1 MEK1 PRKMK1 Breast invasive carcinoma Ubiquitination N K205 Q02750 5604 MAP2K1 MEK1 PRKMK1 Noonan syndrome Ubiquitination N K205 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Ubiquitination N K205 Q02750 5604 MAP2K1 MEK1 PRKMK1 Skin cutaneous melanoma Ubiquitination N K205 Q02750 5604 MAP2K1 MEK1 PRKMK1 Stomach adenocarcinoma Ubiquitination N K205 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N S212 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N S218 Q02750 5604 MAP2K1 MEK1 PRKMK1 Stomach adenocarcinoma Phosphorylation N S218 Q02750 5604 MAP2K1 MEK1 PRKMK1 Stomach adenocarcinoma Phosphorylation N S222 Q02750 5604 MAP2K1 MEK1 PRKMK1 Uterine corpus endometrial carcinoma Phosphorylation N S222 Q02750 5604 MAP2K1 MEK1 PRKMK1 Colon adenocarcinoma Phosphorylation N T226 Q02750 5604 MAP2K1 MEK1 PRKMK1 Stomach adenocarcinoma Phosphorylation N T226 Q02750 5604 MAP2K1 MEK1 PRKMK1 Uterine corpus endometrial carcinoma Phosphorylation N T226 Q02750 5604 MAP2K1 MEK1 PRKMK1 Bladder urothelial carcinoma Phosphorylation N S231 Q02750 5604 MAP2K1 MEK1 PRKMK1 Colon adenocarcinoma Phosphorylation N S231 Q02750 5604 MAP2K1 MEK1 PRKMK1 Stomach adenocarcinoma Phosphorylation N S231 Q02750 5604 MAP2K1 MEK1 PRKMK1 Uterine corpus endometrial carcinoma Phosphorylation N S231 Q02750 5604 MAP2K1 MEK1 PRKMK1 Noonan syndrome Phosphorylation N T286 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N T286 Q02750 5604 MAP2K1 MEK1 PRKMK1 Head and neck squamous cell carcinoma Phosphorylation C T292 Q02750 5604 MAP2K1 MEK1 PRKMK1 Noonan syndrome Phosphorylation N T292 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N T292 Q02750 5604 MAP2K1 MEK1 PRKMK1 Head and neck squamous cell carcinoma Phosphorylation N S298 Q02750 5604 MAP2K1 MEK1 PRKMK1 Noonan syndrome Phosphorylation N S298 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N S298 Q02750 5604 MAP2K1 MEK1 PRKMK1 Uterine corpus endometrial carcinoma Phosphorylation N S298 Q02750 5604 MAP2K1 MEK1 PRKMK1 Head and neck squamous cell carcinoma Phosphorylation N S299 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N S299 Q02750 5604 MAP2K1 MEK1 PRKMK1 Uterine corpus endometrial carcinoma Phosphorylation N S299 Q02750 5604 MAP2K1 MEK1 PRKMK1 Head and neck squamous cell carcinoma Phosphorylation N Y300 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N Y300 Q02750 5604 MAP2K1 MEK1 PRKMK1 Uterine corpus endometrial carcinoma Phosphorylation N Y300 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation C S304 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N S304 Q02750 5604 MAP2K1 MEK1 PRKMK1 Uterine corpus endometrial carcinoma Phosphorylation N S304 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cervical squamous cell carcinoma and endocervical adenocarcinoma Ubiquitination N K344 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Ubiquitination N K344 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cervical squamous cell carcinoma and endocervical adenocarcinoma Ubiquitination N K353 Q02750 5604 MAP2K1 MEK1 PRKMK1 Noonan syndrome Ubiquitination N K353 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Ubiquitination N K353 Q02750 5604 MAP2K1 MEK1 PRKMK1 Cervical squamous cell carcinoma and endocervical adenocarcinoma Acetylation N K362 Q02750 5604 MAP2K1 MEK1 PRKMK1 Noonan syndrome Acetylation N K362 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Acetylation N K362 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N S385 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N T386 Q02750 5604 MAP2K1 MEK1 PRKMK1 Rasopathy Phosphorylation N T388 Q02750 5604 MAP2K1 MEK1 PRKMK1 Endometrial cancer tumor tissue Citrullination U R113 33747724 Q02750 5604 MAP2K1 MEK1 PRKMK1 Endometrial cancer tumor tissue Citrullination U R189 33747724 Q02750 5604 MAP2K1 MEK1 PRKMK1 Breast cancer MCF-10 cells Phosphorylation U 15193230 Q02750 5604 MAP2K1 MEK1 PRKMK1 Pancreatic cancer/carcinoma/adenocarcinoma pancreatic cancer cells Phosphorylation P 24209743 Q02750 5604 MAP2K1 MEK1 PRKMK1 Adenoma Phosphorylation U 21989899 Q02750 5604 MAP2K1 MEK1 PRKMK1 Crohn's disease Phosphorylation U 23970928 Q02750 5604 MAP2K1 MEK1 PRKMK1 Colon cancer/carcinoma Phosphorylation P 15233637 Q02750 5604 MAP2K1 MEK1 PRKMK1 Head and neck squamous cell carcinoma Serine phosphorylation U S218 21281788 Q02750 5604 MAP2K1 MEK1 PRKMK1 Head and neck squamous cell carcinoma Serine phosphorylation U S222 21281788