Uniprot AC Entrez ID Gene Name Disease Cell Type PTM Type State Position PMID P35568 3667 IRS1 Glioblastoma Phosphorylation N Y46 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N Y46 P35568 3667 IRS1 Glioblastoma Phosphorylation N Y47 P35568 3667 IRS1 Glioblastoma Acetylation N K52 P35568 3667 IRS1 Uterine corpus endometrial carcinoma Acetylation N K52 P35568 3667 IRS1 Uterine corpus endometrial carcinoma Acetylation N K61 P35568 3667 IRS1 Breast adenocarcinoma Phosphorylation N Y87 P35568 3667 IRS1 Breast adenocarcinoma Phosphorylation N T88 P35568 3667 IRS1 Breast adenocarcinoma Phosphorylation N S99 P35568 3667 IRS1 Lung cancer Phosphorylation N Y151 P35568 3667 IRS1 Cervical squamous cell carcinoma and endocervical adenocarcinoma Phosphorylation N S268 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N S268 P35568 3667 IRS1 Lung squamous cell carcinoma Phosphorylation N S268 P35568 3667 IRS1 Cervical squamous cell carcinoma and endocervical adenocarcinoma Phosphorylation N S270 P35568 3667 IRS1 Colorectal cancer Phosphorylation N S270 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N S270 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N S272 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N S274 P35568 3667 IRS1 Ovarian adenocarcinoma Phosphorylation N S312 P35568 3667 IRS1 Ovarian adenocarcinoma Phosphorylation N S315 P35568 3667 IRS1 Uterine corpus endometrial carcinoma Phosphorylation N S315 P35568 3667 IRS1 Uterine corpus endometrial carcinoma Phosphorylation C S323 P35568 3667 IRS1 Ovarian adenocarcinoma Phosphorylation N S323 P35568 3667 IRS1 Uterine cancer Phosphorylation N S323 P35568 3667 IRS1 Uterine corpus endometrial carcinoma Phosphorylation N S323 P35568 3667 IRS1 Melanoma Phosphorylation N S329 P35568 3667 IRS1 Prostate adenocarcinoma Phosphorylation N S329 P35568 3667 IRS1 Skin cutaneous melanoma Phosphorylation N S329 P35568 3667 IRS1 Uterine corpus endometrial carcinoma Phosphorylation N S329 P35568 3667 IRS1 Melanoma Phosphorylation N S330 P35568 3667 IRS1 Prostate adenocarcinoma Phosphorylation N S330 P35568 3667 IRS1 Skin cutaneous melanoma Phosphorylation N S330 P35568 3667 IRS1 Uterine cancer Phosphorylation N S330 P35568 3667 IRS1 Uterine corpus endometrial carcinoma Phosphorylation N S330 P35568 3667 IRS1 Melanoma Phosphorylation N T335 P35568 3667 IRS1 Prostate adenocarcinoma Phosphorylation N T335 P35568 3667 IRS1 Skin cutaneous melanoma Phosphorylation N T335 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N T335 P35568 3667 IRS1 Testicular germ cell tumor Phosphorylation N T335 P35568 3667 IRS1 Uterine corpus endometrial carcinoma Phosphorylation N T335 P35568 3667 IRS1 Melanoma Phosphorylation N S341 P35568 3667 IRS1 Skin cutaneous melanoma Phosphorylation N S341 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N S341 P35568 3667 IRS1 Testicular germ cell tumor Phosphorylation N S341 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N S345 P35568 3667 IRS1 Testicular germ cell tumor Phosphorylation N S345 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N S350 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N T351 P35568 3667 IRS1 Bladder urothelial carcinoma Phosphorylation N S362 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N S362 P35568 3667 IRS1 Uterine corpus endometrial carcinoma Phosphorylation N S362 P35568 3667 IRS1 Kidney renal clear cell carcinoma Phosphorylation N S374 P35568 3667 IRS1 Kidney renal clear cell carcinoma Phosphorylation N S383 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N S383 P35568 3667 IRS1 Kidney renal clear cell carcinoma Phosphorylation N S385 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N S385 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation C S388 P35568 3667 IRS1 Kidney renal clear cell carcinoma Phosphorylation N S388 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N S388 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation C S391 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N S391 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N S417 P35568 3667 IRS1 Ovarian adenocarcinoma Phosphorylation N S417 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N S419 P35568 3667 IRS1 Head and neck squamous cell carcinoma Phosphorylation N T495 P35568 3667 IRS1 Skin cutaneous melanoma Phosphorylation N T495 P35568 3667 IRS1 Head and neck squamous cell carcinoma Phosphorylation N T498 P35568 3667 IRS1 Skin cutaneous melanoma Phosphorylation N T498 P35568 3667 IRS1 Head and neck squamous cell carcinoma Phosphorylation N T502 P35568 3667 IRS1 Skin cutaneous melanoma Phosphorylation N T502 P35568 3667 IRS1 Head and neck squamous cell carcinoma Phosphorylation N S503 P35568 3667 IRS1 Skin cutaneous melanoma Phosphorylation N S503 P35568 3667 IRS1 Bladder urothelial carcinoma Phosphorylation N T525 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N T525 P35568 3667 IRS1 Bladder urothelial carcinoma Phosphorylation N S527 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N S527 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N S574 P35568 3667 IRS1 Kidney renal papillary cell carcinoma Phosphorylation N S581 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N S581 P35568 3667 IRS1 Colon adenocarcinoma Phosphorylation N S603 P35568 3667 IRS1 Colorectal adenocarcinoma Phosphorylation N S603 P35568 3667 IRS1 Diabetes mellitus Phosphorylation N S603 P35568 3667 IRS1 Colon adenocarcinoma Phosphorylation N S604 P35568 3667 IRS1 Colorectal adenocarcinoma Phosphorylation N S604 P35568 3667 IRS1 Diabetes mellitus Phosphorylation N S604 P35568 3667 IRS1 Colon adenocarcinoma Phosphorylation N T608 P35568 3667 IRS1 Colorectal adenocarcinoma Phosphorylation N T608 P35568 3667 IRS1 Diabetes mellitus Phosphorylation N T608 P35568 3667 IRS1 Colon adenocarcinoma Phosphorylation N Y612 P35568 3667 IRS1 Colorectal adenocarcinoma Phosphorylation N Y612 P35568 3667 IRS1 Diabetes mellitus Phosphorylation N Y612 P35568 3667 IRS1 Lung cancer Phosphorylation N Y632 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N S666 P35568 3667 IRS1 Breast invasive carcinoma Phosphorylation N Y732 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N Y732 P35568 3667 IRS1 Breast invasive carcinoma Phosphorylation N S736 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N S736 P35568 3667 IRS1 Brain lower grade glioma Phosphorylation N S766 P35568 3667 IRS1 Brain lower grade glioma Methylation N K772 P35568 3667 IRS1 Brain lower grade glioma Ubiquitination N K772 P35568 3667 IRS1 Ovarian adenocarcinoma Phosphorylation N S794 P35568 3667 IRS1 Diabetes mellitus Phosphorylation N T811 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N T811 P35568 3667 IRS1 Pancreatic adenocarcinoma Phosphorylation N S862 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N S862 P35568 3667 IRS1 Skin cutaneous melanoma Phosphorylation N S892 P35568 3667 IRS1 Skin cutaneous melanoma Phosphorylation N Y896 P35568 3667 IRS1 Head and neck squamous cell carcinoma Phosphorylation N Y941 P35568 3667 IRS1 Rectum adenocarcinoma O-linked glycosylation N S984 P35568 3667 IRS1 Rectum adenocarcinoma O-linked glycosylation N S985 P35568 3667 IRS1 Rectum adenocarcinoma Phosphorylation N Y989 P35568 3667 IRS1 Lung cancer Phosphorylation N S1005 P35568 3667 IRS1 Bladder urothelial carcinoma Phosphorylation N S1025 P35568 3667 IRS1 Breast adenocarcinoma Phosphorylation N S1041 P35568 3667 IRS1 Type 2 diabetes mellitus Phosphorylation N S1041 P35568 3667 IRS1 Breast adenocarcinoma Phosphorylation N S1043 P35568 3667 IRS1 Diabetes mellitus Phosphorylation N S1078 P35568 3667 IRS1 Esophageal adenocarcinoma Phosphorylation N S1078 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N S1078 P35568 3667 IRS1 Diabetes mellitus Phosphorylation N S1084 P35568 3667 IRS1 Esophageal adenocarcinoma Phosphorylation N S1084 P35568 3667 IRS1 Stomach adenocarcinoma Phosphorylation N S1084 P35568 3667 IRS1 Type 2 diabetes mellitus Phosphorylation N S1100 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N T1103 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N T1107 P35568 3667 IRS1 Breast adenocarcinoma Phosphorylation N T1111 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N T1111 P35568 3667 IRS1 Lung adenocarcinoma Phosphorylation N Y1179 P35568 3667 IRS1 Non-Hodgkin's lymphoma Phosphorylation N S1222 P35568 3667 IRS1 Non-Hodgkin's lymphoma Phosphorylation N S1223 P36776 9361 LONP1 PRSS15 Head and neck squamous cell carcinoma Phosphorylation N S80 P36776 9361 LONP1 PRSS15 Thyroid carcinoma Phosphorylation N S80 P36776 9361 LONP1 PRSS15 Lung adenocarcinoma Phosphorylation N Y492 P36776 9361 LONP1 PRSS15 Kidney renal clear cell carcinoma Phosphorylation N S548 P36776 9361 LONP1 PRSS15 Lung adenocarcinoma Phosphorylation N S548 P36776 9361 LONP1 PRSS15 Bladder urothelial carcinoma Phosphorylation N T580 P36776 9361 LONP1 PRSS15 Bladder urothelial carcinoma Ubiquitination N K581 P36776 9361 LONP1 PRSS15 Uterine corpus endometrial carcinoma Ubiquitination N K714 P36776 9361 LONP1 PRSS15 CODAS syndrome Succinylation N K748 P36776 9361 LONP1 PRSS15 Stomach adenocarcinoma Phosphorylation N T803 P36776 9361 LONP1 PRSS15 Bladder urothelial carcinoma Phosphorylation N T880 P36776 9361 LONP1 PRSS15 Hepatocellular carcinoma Methylation N R904 Q9Y4H2 8660 IRS2 Pancreatic adenocarcinoma Phosphorylation N Y184 Q9Y4H2 8660 IRS2 Liver cancer Phosphorylation N S306 Q9Y4H2 8660 IRS2 Non-Hodgkin's lymphoma Phosphorylation N S560 Q9Y4H2 8660 IRS2 Non-Hodgkin's lymphoma Methylation N R569 Q9Y4H2 8660 IRS2 Prostate adenocarcinoma Methylation N R569 Q9Y4H2 8660 IRS2 Prostate adenocarcinoma Phosphorylation N T575 Q9Y4H2 8660 IRS2 Prostate adenocarcinoma Phosphorylation N Y576 Q9Y4H2 8660 IRS2 Prostate adenocarcinoma Phosphorylation N S577 Q9Y4H2 8660 IRS2 Hepatocellular carcinoma Phosphorylation N T579 Q9Y4H2 8660 IRS2 Melanoma Phosphorylation N T579 Q9Y4H2 8660 IRS2 Prostate adenocarcinoma Phosphorylation N T579 Q9Y4H2 8660 IRS2 Hepatocellular carcinoma Phosphorylation N T580 Q9Y4H2 8660 IRS2 Liver cancer Phosphorylation N T580 Q9Y4H2 8660 IRS2 Hepatocellular carcinoma Phosphorylation N S591 Q9Y4H2 8660 IRS2 Hepatocellular carcinoma Phosphorylation N S592 Q9Y4H2 8660 IRS2 Pancreatic adenocarcinoma Phosphorylation N S608 Q9Y4H2 8660 IRS2 Pancreatic adenocarcinoma Phosphorylation N S615 Q9Y4H2 8660 IRS2 Pancreatic adenocarcinoma Phosphorylation N S619 Q9Y4H2 8660 IRS2 Pancreatic adenocarcinoma Phosphorylation N S620 Q9Y4H2 8660 IRS2 Skin cutaneous melanoma Phosphorylation N Y625 Q9Y4H2 8660 IRS2 Bladder urothelial carcinoma Phosphorylation N Y628 Q9Y4H2 8660 IRS2 Skin cutaneous melanoma Phosphorylation N Y628 Q9Y4H2 8660 IRS2 Bladder urothelial carcinoma Phosphorylation N Y632 Q9Y4H2 8660 IRS2 Skin cutaneous melanoma Phosphorylation N Y632 Q9Y4H2 8660 IRS2 Bladder urothelial carcinoma Phosphorylation N S639 Q9Y4H2 8660 IRS2 Thyroid carcinoma Phosphorylation N S682 Q9Y4H2 8660 IRS2 Pancreatic adenocarcinoma Phosphorylation N S723 Q9Y4H2 8660 IRS2 Thyroid carcinoma Phosphorylation N S752 Q9Y4H2 8660 IRS2 Melanoma Phosphorylation N S770 Q9Y4H2 8660 IRS2 Head and neck squamous cell carcinoma Phosphorylation N T776 Q9Y4H2 8660 IRS2 Head and neck squamous cell carcinoma Phosphorylation N T777 Q9Y4H2 8660 IRS2 Head and neck squamous cell carcinoma Phosphorylation N T779 Q9Y4H2 8660 IRS2 Colon adenocarcinoma Phosphorylation N Y803 Q9Y4H2 8660 IRS2 Colon adenocarcinoma Phosphorylation N S804 Q9Y4H2 8660 IRS2 Colon adenocarcinoma Phosphorylation N S805 Q9Y4H2 8660 IRS2 Colon adenocarcinoma Phosphorylation N S809 Q9Y4H2 8660 IRS2 Colon adenocarcinoma Phosphorylation N Y810 Q9Y4H2 8660 IRS2 Glioblastoma Phosphorylation N S932 Q9Y4H2 8660 IRS2 Thyroid carcinoma Phosphorylation N S973 Q9Y4H2 8660 IRS2 Lung cancer Phosphorylation N T1082 Q9Y4H2 8660 IRS2 Thyroid carcinoma Phosphorylation N T1082 Q9Y4H2 8660 IRS2 Breast cancer Phosphorylation N S1162 Q9Y4H2 8660 IRS2 Stomach adenocarcinoma Phosphorylation N S1174 Q9Y4H2 8660 IRS2 Stomach cancer Phosphorylation N S1174 Q9Y4H2 8660 IRS2 Stomach adenocarcinoma Phosphorylation N S1176 Q9Y4H2 8660 IRS2 Stomach adenocarcinoma Phosphorylation N S1181 Q9Y4H2 8660 IRS2 Stomach adenocarcinoma Phosphorylation N S1185 Q9Y4H2 8660 IRS2 Stomach adenocarcinoma Phosphorylation N S1186 Q9Y4H2 8660 IRS2 Bladder urothelial carcinoma Phosphorylation N T1221 Q9Y4H2 8660 IRS2 Stomach adenocarcinoma Phosphorylation N T1221 Q9Y4H2 8660 IRS2 Head and neck squamous cell carcinoma Phosphorylation N S1234 Q9Y4H2 8660 IRS2 Hepatocellular carcinoma Phosphorylation N S1234 Q9Y4H2 8660 IRS2 Head and neck squamous cell carcinoma Phosphorylation N S1237 Q9Y4H2 8660 IRS2 Hepatocellular carcinoma Phosphorylation N S1237 Q9Y4H2 8660 IRS2 Head and neck squamous cell carcinoma Phosphorylation N T1243 Q9Y4H2 8660 IRS2 Hepatocellular carcinoma Phosphorylation N T1243 Q9Y4H2 8660 IRS2 Lung adenocarcinoma Phosphorylation N T1243 P35568 3667 IRS1 Diabetes mellitus L6 skeletal muscle cell Serine phosphorylation U S1101 17709744 P35568 3667 IRS1 Ductal carcinoma in situ tumor tissue Phosphorylation U 23562473 P36776 9361 LONP1 PRSS15 Polycystic ovary syndrome ovarian tissue Decrotonylation U K390 37817894 P35568 3667 IRS1 Hepatocellular carcinoma/hepatocarcinoma/hepatoma Phosphorylation U 7542850 P35568 3667 IRS1 Primitive neuroectodermal tumor Phosphorylation D 8746448 P35568 3667 IRS1 Polycystic ovary syndrome Phosphorylation D 15130378 Q9Y4H2 8660 IRS2 Polycystic ovary syndrome Phosphorylation D 15840293 P35568 3667 IRS1 Lung cancer/carcinoma Serine phosphorylation P S307 22348039 P35568 3667 IRS1 Non-small cell lung cancer/carcinoma Serine phosphorylation D S616 18687633 P35568 3667 IRS1 Head and neck squamous cell carcinoma Serine phosphorylation U S616 21281788 P35568 3667 IRS1 Diabetes mellitus Serine phosphorylation U S636 12765939 P35568 3667 IRS1 Pancreatic ductal adenocarcinoma Serine phosphorylation U S636 27014871 Q9Y4H2 8660 IRS2 Obesity Serine phosphorylation P S388 26657864 Q9Y4H2 8660 IRS2 Lung cancer Serine phosphorylation U S1100 25297629 Q9Y4H2 8660 IRS2 Melanoma Serine phosphorylation U S1100 17001009 Q9Y4H2 8660 IRS2 Ovarian cancer/carcinoma Serine phosphorylation U S1100 17001009