Uniprot AC Entrez ID Gene Name Disease Cell Type PTM Type State Position PMID P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Hepatocellular carcinoma Phosphorylation N S29 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Hepatocellular carcinoma Phosphorylation N S41 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Lung adenocarcinoma Ubiquitination N K99 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Uterine corpus endometrial carcinoma Ubiquitination N K99 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Cervical squamous cell carcinoma and endocervical adenocarcinoma Ubiquitination N K138 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Hepatocellular carcinoma Ubiquitination N K138 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Inborn genetic diseases Ubiquitination N K138 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Melanoma Ubiquitination N K138 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Skin cutaneous melanoma Ubiquitination N K138 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Stomach adenocarcinoma Ubiquitination N K138 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Cervical squamous cell carcinoma and endocervical adenocarcinoma Phosphorylation N S142 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Hepatocellular carcinoma Phosphorylation N S142 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Inborn genetic diseases Phosphorylation N S142 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Kidney renal papillary cell carcinoma Phosphorylation N S142 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Melanoma Phosphorylation N S142 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Skin cutaneous melanoma Phosphorylation N S142 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Stomach adenocarcinoma Phosphorylation N S142 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Hepatocellular carcinoma Ubiquitination N K151 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Kidney renal papillary cell carcinoma Ubiquitination N K151 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Lung squamous cell carcinoma Ubiquitination N K164 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Adrenocortical carcinoma Phosphorylation N T181 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Liver cancer Phosphorylation N T181 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Adrenocortical carcinoma Phosphorylation N T185 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Liver cancer Phosphorylation N T185 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Medulloblastoma Phosphorylation N T185 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Prostate adenocarcinoma Phosphorylation N T185 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Stomach adenocarcinoma Phosphorylation N T185 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Medulloblastoma Phosphorylation N Y187 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Prostate adenocarcinoma Phosphorylation N Y187 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Stomach adenocarcinoma Phosphorylation N Y187 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Medulloblastoma Phosphorylation N T190 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Prostate adenocarcinoma Phosphorylation N T190 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Stomach adenocarcinoma Phosphorylation N T190 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Medulloblastoma Phosphorylation N Y193 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Pancreatic adenocarcinoma Phosphorylation N Y193 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Prostate adenocarcinoma Phosphorylation N Y193 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Stomach adenocarcinoma Phosphorylation N Y193 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Medulloblastoma Methylation N R194 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Pancreatic adenocarcinoma Methylation N R194 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Prostate adenocarcinoma Methylation N R194 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Stomach adenocarcinoma Methylation N R194 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Pancreatic adenocarcinoma Phosphorylation N S202 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Pancreatic adenocarcinoma Ubiquitination N K203 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Pancreatic adenocarcinoma Phosphorylation N Y205 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Glioblastoma multiforme Phosphorylation N S246 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Glioblastoma multiforme Phosphorylation N S248 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Brain lower grade glioma Ubiquitination N K259 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Glioblastoma multiforme Ubiquitination N K259 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Kidney renal clear cell carcinoma Ubiquitination N K259 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Brain lower grade glioma Phosphorylation N Y263 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Glioblastoma multiforme Phosphorylation N Y263 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Kidney renal clear cell carcinoma Phosphorylation N Y263 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Brain lower grade glioma Ubiquitination N K270 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Breast invasive carcinoma Ubiquitination N K330 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Clear cell renal cell carcinoma tumor tissue Phosphorylation U 36966163 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Colorectal cancer tumor tissue Dephosphorylation D 36526622 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Hepatocellular carcinoma tumor tissue Tyrosine phosphorylation U Y204 36230524 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Pancreatic cancer pancreatic cancer cells Phosphorylation U 21678462 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Glioblastoma tumor tissue Phosphorylation U 23115159 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Ovarian cancer/carcinoma tumor tissue Phosphorylation U 23285101 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Liver cancer SK-hep-1 cell line Phosphorylation P 23693078 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Colon cancer/carcinoma tumor tissue Phosphorylation P 23183114 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Lymphoma cell line Phosphorylation U 23620775 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Osteosarcoma tumor tissue Phosphorylation U 31383289 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Clear cell renal cell carcinoma A498 cells Phosphorylation U 37454877 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Glioblastoma tumor tissue Phosphorylation U 36493392 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Triple-negative breast cancer breast cancer cells Tyrosine phosphorylation U Y187 28415597 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Pulmonary emphysema lung tissues Threonine phosphorylation U T202 14764579 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Pulmonary emphysema lung tissues Tyrosine phosphorylation U Y204 14764579 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Colon cancer/carcinoma Phosphorylation A 23786838 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Neuroblastoma Phosphorylation U 15972965 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Adenoma Phosphorylation U 21989899 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Breast cancer/tumor/carcinoma Phosphorylation U 10216485 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Prostate cancer/carcinoma/adenocarcinoma Phosphorylation U 9927031 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Myelodysplasia Phosphorylation D 12529294 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Pulmonary carcinoid Phosphorylation D 15956248 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Squamous cell carcinoma of the larynx Phosphorylation D 16865246 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Lung cancer/carcinoma Phosphorylation U 24286320 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Bipolar disorder Phosphorylation U 24075327 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Crohn's disease Phosphorylation U 23970928 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Acute myeloid leukemia/acute myelogenous leukemia Phosphorylation P 23840454 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Non-small cell lung cancer/carcinoma Phosphorylation P 24096476 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Bladder cancer Phosphorylation P 24375195 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Astrocytoma/astrocytoma glioblastoma Phosphorylation P 17327470 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Thyroid cancer/carcinoma Phosphorylation P 11299771 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Brain cancer Phosphorylation P 12388552 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Rhabdomyosarcoma Phosphorylation P 14633723 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Choriocarcinoma Serine phosphorylation U S41 11466319 P28482 5594 MAPK1 ERK2 PRKM1 PRKM2 Thyroid cancer/carcinoma Tyrosine phosphorylation U Y187 17209045