Uniprot AC Entrez ID Gene Name Disease Cell Type PTM Type State Position PMID P27361 5595 MAPK3 ERK1 PRKM3 Bladder urothelial carcinoma Ubiquitination N K72 P27361 5595 MAPK3 ERK1 PRKM3 Bladder urothelial carcinoma Phosphorylation N T80 P27361 5595 MAPK3 ERK1 PRKM3 Skin cutaneous melanoma Phosphorylation N T80 P27361 5595 MAPK3 ERK1 PRKM3 Uterine corpus endometrial carcinoma Phosphorylation N T80 P27361 5595 MAPK3 ERK1 PRKM3 Breast invasive carcinoma Ubiquitination N K155 P27361 5595 MAPK3 ERK1 PRKM3 Stomach adenocarcinoma Ubiquitination N K155 P27361 5595 MAPK3 ERK1 PRKM3 Breast invasive carcinoma Phosphorylation N S159 P27361 5595 MAPK3 ERK1 PRKM3 Bladder urothelial carcinoma Ubiquitination N K181 P27361 5595 MAPK3 ERK1 PRKM3 Uterine cancer Phosphorylation N T198 P27361 5595 MAPK3 ERK1 PRKM3 Colon adenocarcinoma Phosphorylation N Y204 P27361 5595 MAPK3 ERK1 PRKM3 Lung cancer Phosphorylation N Y204 P27361 5595 MAPK3 ERK1 PRKM3 Colon adenocarcinoma Phosphorylation N T207 P27361 5595 MAPK3 ERK1 PRKM3 Lung adenocarcinoma Phosphorylation N T207 P27361 5595 MAPK3 ERK1 PRKM3 Colon adenocarcinoma Phosphorylation N Y210 P27361 5595 MAPK3 ERK1 PRKM3 Lung adenocarcinoma Phosphorylation N Y210 P27361 5595 MAPK3 ERK1 PRKM3 Colon adenocarcinoma Methylation N R211 P27361 5595 MAPK3 ERK1 PRKM3 Lung adenocarcinoma Methylation N R211 P27361 5595 MAPK3 ERK1 PRKM3 Lung adenocarcinoma Phosphorylation N S219 P27361 5595 MAPK3 ERK1 PRKM3 Lung adenocarcinoma Ubiquitination N K220 P27361 5595 MAPK3 ERK1 PRKM3 Skin cutaneous melanoma Ubiquitination N K294 P27361 5595 MAPK3 ERK1 PRKM3 Skin cutaneous melanoma Ubiquitination N K298 P27361 5595 MAPK3 ERK1 PRKM3 Skin cutaneous melanoma Methylation N K302 P27361 5595 MAPK3 ERK1 PRKM3 Skin cutaneous melanoma Ubiquitination N K302 P27361 5595 MAPK3 ERK1 PRKM3 Lung squamous cell carcinoma Methylation N R309 P27361 5595 MAPK3 ERK1 PRKM3 Skin cutaneous melanoma Methylation N R309 P27361 5595 MAPK3 ERK1 PRKM3 Lung squamous cell carcinoma Ubiquitination N K317 P27361 5595 MAPK3 ERK1 PRKM3 Glioblastoma multiforme SUMOylation N K357 P27361 5595 MAPK3 ERK1 PRKM3 Glioblastoma multiforme Ubiquitination N K357 P27361 5595 MAPK3 ERK1 PRKM3 Glioblastoma multiforme Methylation N K361 P27361 5595 MAPK3 ERK1 PRKM3 Stomach adenocarcinoma Methylation N K361 P27361 5595 MAPK3 ERK1 PRKM3 Glioblastoma multiforme Ubiquitination N K361 P27361 5595 MAPK3 ERK1 PRKM3 Stomach adenocarcinoma Ubiquitination N K361 P31751 208 AKT2 Hypoinsulinemic hypoglycemia with hemihypertrophy Ubiquitination N K14 P31751 208 AKT2 Lung squamous cell carcinoma Ubiquitination N K14 P31751 208 AKT2 Thyroid carcinoma Ubiquitination N K14 P31751 208 AKT2 Hypoinsulinemic hypoglycemia with hemihypertrophy Ubiquitination N K20 P31751 208 AKT2 Lung squamous cell carcinoma Ubiquitination N K20 P31751 208 AKT2 Stomach adenocarcinoma Ubiquitination N K20 P31751 208 AKT2 Thyroid carcinoma Ubiquitination N K20 P31751 208 AKT2 Cervical squamous cell carcinoma and endocervical adenocarcinoma Ubiquitination N K30 P31751 208 AKT2 Stomach adenocarcinoma Ubiquitination N K30 P31751 208 AKT2 Cervical squamous cell carcinoma and endocervical adenocarcinoma Phosphorylation N S34 P31751 208 AKT2 Cervical squamous cell carcinoma and endocervical adenocarcinoma Ubiquitination N K39 P31751 208 AKT2 Diabetes mellitus Ubiquitination N K39 P31751 208 AKT2 Diabetes mellitus Ubiquitination N K111 P31751 208 AKT2 Diabetes mellitus Phosphorylation N Y122 P31751 208 AKT2 Lung squamous cell carcinoma Phosphorylation N Y122 P31751 208 AKT2 Lung squamous cell carcinoma Phosphorylation N S126 P31751 208 AKT2 Colon adenocarcinoma Phosphorylation N S128 P31751 208 AKT2 Colon adenocarcinoma Phosphorylation N S131 P31751 208 AKT2 Melanoma Ubiquitination N K156 P31751 208 AKT2 Skin cutaneous melanoma Ubiquitination N K156 P31751 208 AKT2 Melanoma Ubiquitination N K160 P31751 208 AKT2 Skin cutaneous melanoma Ubiquitination N K160 P31751 208 AKT2 Bladder urothelial carcinoma Ubiquitination N K185 P31751 208 AKT2 Diabetes mellitus Ubiquitination N K185 P31751 208 AKT2 Stomach adenocarcinoma Ubiquitination N K185 P31751 208 AKT2 Diabetes mellitus Ubiquitination N K191 P31751 208 AKT2 Rectum adenocarcinoma Ubiquitination N K191 P31751 208 AKT2 Stomach adenocarcinoma Ubiquitination N K191 P31751 208 AKT2 Diabetes mellitus Ubiquitination N K277 P31751 208 AKT2 Kidney renal papillary cell carcinoma Ubiquitination N K277 P31751 208 AKT2 Skin cutaneous melanoma Ubiquitination N K277 P31751 208 AKT2 Breast invasive carcinoma Ubiquitination N K285 P31751 208 AKT2 Breast invasive carcinoma Ubiquitination N K290 P31751 208 AKT2 Liver cancer Phosphorylation N T309 P31751 208 AKT2 Uterine corpus endometrial carcinoma Phosphorylation N T309 P31751 208 AKT2 Uterine corpus endometrial carcinoma Phosphorylation N T313 P31751 208 AKT2 Uterine corpus endometrial carcinoma Phosphorylation N Y316 P31751 208 AKT2 Lymphoid neoplasm diffuse large B-cell lymphoma Ubiquitination N K378 P31751 208 AKT2 Bladder urothelial carcinoma Ubiquitination N K401 P31751 208 AKT2 Lung adenocarcinoma Ubiquitination N K401 P31751 208 AKT2 Cervical squamous cell carcinoma and endocervical adenocarcinoma Ubiquitination N K427 P31751 208 AKT2 Kidney renal papillary cell carcinoma Ubiquitination N K427 P31751 208 AKT2 Lung adenocarcinoma Phosphorylation N S447 P31751 208 AKT2 Melanoma Phosphorylation N S447 P31751 208 AKT2 Sarcoma Phosphorylation N S447 P31751 208 AKT2 Skin cutaneous melanoma Phosphorylation N S447 P31751 208 AKT2 Diabetes mellitus Phosphorylation N T449 P31751 208 AKT2 Lung adenocarcinoma Phosphorylation N T449 P31751 208 AKT2 Sarcoma Phosphorylation N T449 P31751 208 AKT2 Skin cutaneous melanoma Phosphorylation N T449 P31751 208 AKT2 Diabetes mellitus Phosphorylation N T451 P31751 208 AKT2 Lung adenocarcinoma Phosphorylation N T451 P31751 208 AKT2 Sarcoma Phosphorylation N T451 P31751 208 AKT2 Skin cutaneous melanoma Phosphorylation N T451 P31751 208 AKT2 Bladder urothelial carcinoma Phosphorylation N S458 P31751 208 AKT2 Diabetes mellitus Phosphorylation N S458 P31751 208 AKT2 Sarcoma Phosphorylation N S458 P31751 208 AKT2 Head and neck squamous cell carcinoma Phosphorylation N S474 P31751 208 AKT2 Head and neck squamous cell carcinoma Phosphorylation N Y475 P31751 208 AKT2 Head and neck squamous cell carcinoma Phosphorylation N S476 P31751 208 AKT2 Head and neck squamous cell carcinoma Phosphorylation N S478 P27361 5595 MAPK3 ERK1 PRKM3 Lung cancer lung cancer cells Phosphorylation U 34439211 P31751 208 AKT2 Cancer tumor tissue Lysine methylation U 30692625 P27361 5595 MAPK3 ERK1 PRKM3 Colorectal cancer tumor tissue Dephosphorylation D 36526622 P27361 5595 MAPK3 ERK1 PRKM3 Non-small cell lung cancer tumor tissue Dephosphorylation A 36966223 P27361 5595 MAPK3 ERK1 PRKM3 Breast cancer breast cancer tissues Threonine phosphorylation U T202 31944568 P27361 5595 MAPK3 ERK1 PRKM3 Hepatocellular carcinoma tumor tissue Threonine phosphorylation U T202 36230524 P27361 5595 MAPK3 ERK1 PRKM3 Breast cancer breast cancer tissues Tyrosine phosphorylation U Y204 31944568 P27361 5595 MAPK3 ERK1 PRKM3 Pancreatic cancer pancreatic cancer cells Phosphorylation U 21678462 P27361 5595 MAPK3 ERK1 PRKM3 Ovarian cancer/carcinoma tumor tissue Phosphorylation U 14961570 P27361 5595 MAPK3 ERK1 PRKM3 Breast cancer MCF-10 cells Phosphorylation U 15193230 P27361 5595 MAPK3 ERK1 PRKM3 Ovarian cancer/carcinoma tumor tissue Phosphorylation U 23285101 P27361 5595 MAPK3 ERK1 PRKM3 Liver cancer SK-hep-1 cell line Phosphorylation P 23693078 P27361 5595 MAPK3 ERK1 PRKM3 Colon cancer/carcinoma tumor tissue Phosphorylation P 23183114 P27361 5595 MAPK3 ERK1 PRKM3 Colon cancer/carcinoma tumor tissue Phosphorylation P 24085800 P27361 5595 MAPK3 ERK1 PRKM3 Pancreatic cancer/carcinoma/adenocarcinoma pancreatic cancer cells Phosphorylation P 24209743 P27361 5595 MAPK3 ERK1 PRKM3 Lymphoma cell line Phosphorylation U 23620775 P27361 5595 MAPK3 ERK1 PRKM3 Osteosarcoma tumor tissue Phosphorylation U 31383289 P27361 5595 MAPK3 ERK1 PRKM3 Clear cell renal cell carcinoma A498 cells Phosphorylation U 37454877 P27361 5595 MAPK3 ERK1 PRKM3 Glioblastoma tumor tissue Phosphorylation U 36493392 P27361 5595 MAPK3 ERK1 PRKM3 Pulmonary emphysema lung tissues Threonine phosphorylation U T202 14764579 P27361 5595 MAPK3 ERK1 PRKM3 Pulmonary emphysema lung tissues Tyrosine phosphorylation U Y204 14764579 P27361 5595 MAPK3 ERK1 PRKM3 Triple-negative breast cancer breast cancer cells Tyrosine phosphorylation U Y204 28415597 P27361 5595 MAPK3 ERK1 PRKM3 Tuberous sclerosis complex HEK293T Tyrosine phosphorylation U Y204 17671177 P31751 208 AKT2 Breast cancer breast cancer cell Serine phosphorylation U S474 11507039 P31751 208 AKT2 Ovarian cancer ovarian cancer cells Serine phosphorylation U S474 10822383;10822383 P27361 5595 MAPK3 ERK1 PRKM3 Colon cancer/carcinoma Phosphorylation A 23786838 P27361 5595 MAPK3 ERK1 PRKM3 Recessive parkinson disease Phosphorylation A 23261939 P31751 208 AKT2 Recessive parkinson disease Phosphorylation A 23261939 P31751 208 AKT2 Breast cancer/tumor/carcinoma Phosphorylation D 24425749 P27361 5595 MAPK3 ERK1 PRKM3 Adenoma Phosphorylation U 21989899 P27361 5595 MAPK3 ERK1 PRKM3 Bipolar disorder Phosphorylation U 24075327 P27361 5595 MAPK3 ERK1 PRKM3 Lung cancer/carcinoma Phosphorylation U 24286320 P27361 5595 MAPK3 ERK1 PRKM3 Breast cancer/tumor/carcinoma Phosphorylation U 24374773 P27361 5595 MAPK3 ERK1 PRKM3 Crohn's disease Phosphorylation U 23970928 P31751 208 AKT2 Cancer cachexia/cachexia/cachectic tumor Phosphorylation P 23268279 P27361 5595 MAPK3 ERK1 PRKM3 Non-small cell lung cancer/carcinoma Phosphorylation P 23306155 P27361 5595 MAPK3 ERK1 PRKM3 Non-small cell lung cancer/carcinoma Phosphorylation P 24096476 P27361 5595 MAPK3 ERK1 PRKM3 Bladder cancer Phosphorylation P 24375195 P27361 5595 MAPK3 ERK1 PRKM3 Prostate cancer/carcinoma/adenocarcinoma Phosphorylation P 9927031 P27361 5595 MAPK3 ERK1 PRKM3 Myeloma Phosphorylation P 11986233 P31751 208 AKT2 Rhabdomyosarcoma Phosphorylation P 14633723 P27361 5595 MAPK3 ERK1 PRKM3 Acute lymphocytic leukemia Threonine phosphorylation D T202 26073130 P27361 5595 MAPK3 ERK1 PRKM3 Head and neck squamous cell carcinoma Threonine phosphorylation D T202 21281788 P27361 5595 MAPK3 ERK1 PRKM3 Acute myelogenous leukemia Threonine phosphorylation U T202 26073130 P27361 5595 MAPK3 ERK1 PRKM3 Alzheimer's disease Threonine phosphorylation U T202 35847683 P27361 5595 MAPK3 ERK1 PRKM3 Glioma Threonine phosphorylation U T202 33820494 P27361 5595 MAPK3 ERK1 PRKM3 Acute lymphocytic leukemia Tyrosine phosphorylation D Y204 26073130 P27361 5595 MAPK3 ERK1 PRKM3 Head and neck squamous cell carcinoma Tyrosine phosphorylation D Y204 21281788 P27361 5595 MAPK3 ERK1 PRKM3 Acute myelogenous leukemia Tyrosine phosphorylation U Y204 26073130 P27361 5595 MAPK3 ERK1 PRKM3 Alzheimer's disease Tyrosine phosphorylation U Y204 35847683 P27361 5595 MAPK3 ERK1 PRKM3 Glioma Tyrosine phosphorylation U Y204 33820494 P31751 208 AKT2 Ovarian cancer/carcinoma Serine phosphorylation U S474 14597629