Uniprot AC Entrez ID Gene Name Disease Cell Type PTM Type State Position PMID O43818 9136 RRP9 RNU3IP2 U355K Breast cancer Acetylation N K12 O43818 9136 RRP9 RNU3IP2 U355K Ovarian adenocarcinoma Phosphorylation N S50 O43818 9136 RRP9 RNU3IP2 U355K Prostate adenocarcinoma Phosphorylation N S50 O43818 9136 RRP9 RNU3IP2 U355K Ovarian adenocarcinoma Phosphorylation N S51 O43818 9136 RRP9 RNU3IP2 U355K Prostate adenocarcinoma Phosphorylation N S51 O43818 9136 RRP9 RNU3IP2 U355K Prostate adenocarcinoma Phosphorylation N S53 O43818 9136 RRP9 RNU3IP2 U355K Prostate adenocarcinoma Phosphorylation N S55 O43818 9136 RRP9 RNU3IP2 U355K Lung adenocarcinoma Phosphorylation N T74 O43818 9136 RRP9 RNU3IP2 U355K Kidney renal papillary cell carcinoma Ubiquitination N K125 O43818 9136 RRP9 RNU3IP2 U355K Lung squamous cell carcinoma Ubiquitination N K180 O43818 9136 RRP9 RNU3IP2 U355K Uterine corpus endometrial carcinoma Ubiquitination N K180 O43818 9136 RRP9 RNU3IP2 U355K Stomach adenocarcinoma Phosphorylation N S245 O43818 9136 RRP9 RNU3IP2 U355K Colon adenocarcinoma Ubiquitination N K355 O43818 9136 RRP9 RNU3IP2 U355K Pancreatic adenocarcinoma Ubiquitination N K355 O43818 9136 RRP9 RNU3IP2 U355K Bladder urothelial carcinoma Phosphorylation N S475 O43818 9136 RRP9 RNU3IP2 U355K Skin cutaneous melanoma Phosphorylation N S475 P10276 5914 RARA NR1B1 Uterine corpus endometrial carcinoma Phosphorylation N S74 P10276 5914 RARA NR1B1 Uterine corpus endometrial carcinoma Phosphorylation N S77 P10276 5914 RARA NR1B1 Lung adenocarcinoma SUMOylation N K166 P10276 5914 RARA NR1B1 Lung adenocarcinoma SUMOylation N K171 P10276 5914 RARA NR1B1 Rectum adenocarcinoma Ubiquitination N K190 P10276 5914 RARA NR1B1 Bladder urothelial carcinoma Phosphorylation N S219 P10276 5914 RARA NR1B1 Cervical squamous cell carcinoma Phosphorylation N S219 P10276 5914 RARA NR1B1 Cervical squamous cell carcinoma and endocervical adenocarcinoma Phosphorylation N S219 P10276 5914 RARA NR1B1 Colorectal cancer Phosphorylation N S219 P10276 5914 RARA NR1B1 Hepatocellular carcinoma Phosphorylation N S219 P10276 5914 RARA NR1B1 Melanoma Phosphorylation N S219 P10276 5914 RARA NR1B1 Skin cutaneous melanoma Phosphorylation N S219 P10276 5914 RARA NR1B1 Stomach adenocarcinoma Phosphorylation N S219 P10276 5914 RARA NR1B1 Breast invasive carcinoma Phosphorylation N S369 P10276 5914 RARA NR1B1 Uterine cancer Phosphorylation N S369 P10276 5914 RARA NR1B1 Hepatocellular carcinoma SUMOylation N K399 P10276 5914 RARA NR1B1 Uterine corpus endometrial carcinoma SUMOylation N K399 P10276 5914 RARA NR1B1 Pancreatic adenocarcinoma Phosphorylation N S461 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Acetylation N T2 Q06124 5781 PTPN11 PTP2C SHPTP2 Leukemia Phosphorylation N T59 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N T59 Q06124 5781 PTPN11 PTP2C SHPTP2 Colon adenocarcinoma Phosphorylation N Y62 Q06124 5781 PTPN11 PTP2C SHPTP2 Glioblastoma Phosphorylation N Y62 Q06124 5781 PTPN11 PTP2C SHPTP2 Glioblastoma multiforme Phosphorylation N Y62 Q06124 5781 PTPN11 PTP2C SHPTP2 Juvenile myelomonocytic leukemia Phosphorylation N Y62 Q06124 5781 PTPN11 PTP2C SHPTP2 Leukemia Phosphorylation N Y62 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N Y62 Q06124 5781 PTPN11 PTP2C SHPTP2 Rasopathy Phosphorylation N Y62 Q06124 5781 PTPN11 PTP2C SHPTP2 Colon adenocarcinoma Phosphorylation N Y63 Q06124 5781 PTPN11 PTP2C SHPTP2 Glioblastoma Phosphorylation N Y63 Q06124 5781 PTPN11 PTP2C SHPTP2 Glioblastoma multiforme Phosphorylation N Y63 Q06124 5781 PTPN11 PTP2C SHPTP2 Juvenile myelomonocytic leukemia Phosphorylation N Y63 Q06124 5781 PTPN11 PTP2C SHPTP2 Leukemia Phosphorylation N Y63 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N Y63 Q06124 5781 PTPN11 PTP2C SHPTP2 Rasopathy Phosphorylation N Y63 Q06124 5781 PTPN11 PTP2C SHPTP2 Acute myeloid leukemia Phosphorylation N Y66 Q06124 5781 PTPN11 PTP2C SHPTP2 Brain lower grade glioma Phosphorylation N Y66 Q06124 5781 PTPN11 PTP2C SHPTP2 Colon adenocarcinoma Phosphorylation N Y66 Q06124 5781 PTPN11 PTP2C SHPTP2 Glioblastoma Phosphorylation N Y66 Q06124 5781 PTPN11 PTP2C SHPTP2 Glioblastoma multiforme Phosphorylation N Y66 Q06124 5781 PTPN11 PTP2C SHPTP2 Juvenile myelomonocytic leukemia Phosphorylation N Y66 Q06124 5781 PTPN11 PTP2C SHPTP2 Leukemia Phosphorylation N Y66 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N Y66 Q06124 5781 PTPN11 PTP2C SHPTP2 Rasopathy Phosphorylation N Y66 Q06124 5781 PTPN11 PTP2C SHPTP2 Acute myeloid leukemia Phosphorylation N T73 Q06124 5781 PTPN11 PTP2C SHPTP2 Leukemia Phosphorylation N T73 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N T73 Q06124 5781 PTPN11 PTP2C SHPTP2 Leukemia Phosphorylation N Y80 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N Y80 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N S142 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Acetylation N K198 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Ubiquitination N K260 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N Y263 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N S264 Q06124 5781 PTPN11 PTP2C SHPTP2 LEOPARD syndrome Acetylation N K274 Q06124 5781 PTPN11 PTP2C SHPTP2 LEOPARD syndrome Acetylation N K276 Q06124 5781 PTPN11 PTP2C SHPTP2 Glioblastoma multiforme Phosphorylation N Y279 Q06124 5781 PTPN11 PTP2C SHPTP2 Hepatocellular carcinoma Phosphorylation N Y279 Q06124 5781 PTPN11 PTP2C SHPTP2 LEOPARD syndrome Phosphorylation N Y279 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N Y279 Q06124 5781 PTPN11 PTP2C SHPTP2 Rasopathy Phosphorylation N Y279 Q06124 5781 PTPN11 PTP2C SHPTP2 Glioblastoma multiforme Acetylation N K280 Q06124 5781 PTPN11 PTP2C SHPTP2 Hepatocellular carcinoma Acetylation N K280 Q06124 5781 PTPN11 PTP2C SHPTP2 LEOPARD syndrome Acetylation N K280 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Acetylation N K280 Q06124 5781 PTPN11 PTP2C SHPTP2 Rasopathy Acetylation N K280 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N Y304 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N T411 Q06124 5781 PTPN11 PTP2C SHPTP2 LEOPARD syndrome Phosphorylation N S460 Q06124 5781 PTPN11 PTP2C SHPTP2 LEOPARD syndrome Phosphorylation N T466 Q06124 5781 PTPN11 PTP2C SHPTP2 LEOPARD syndrome Phosphorylation N Y511 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N Y511 Q06124 5781 PTPN11 PTP2C SHPTP2 LEOPARD syndrome Phosphorylation N Y515 Q06124 5781 PTPN11 PTP2C SHPTP2 Rasopathy Phosphorylation N Y542 Q06124 5781 PTPN11 PTP2C SHPTP2 Lung adenocarcinoma Phosphorylation N S558 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N S558 Q06124 5781 PTPN11 PTP2C SHPTP2 Rasopathy Phosphorylation N S558 Q06124 5781 PTPN11 PTP2C SHPTP2 Uterine corpus endometrial carcinoma Phosphorylation N S558 Q06124 5781 PTPN11 PTP2C SHPTP2 Noonan syndrome Phosphorylation N T564 Q06124 5781 PTPN11 PTP2C SHPTP2 Arrhythmogenic right ventricular cardiomyopathy Phosphorylation N S576 Q06124 5781 PTPN11 PTP2C SHPTP2 Hepatocellular carcinoma Phosphorylation N S576 Q06124 5781 PTPN11 PTP2C SHPTP2 Hiatal hernia Phosphorylation N S576 Q06124 5781 PTPN11 PTP2C SHPTP2 Rasopathy Phosphorylation N S576 Q06124 5781 PTPN11 PTP2C SHPTP2 Hepatocellular carcinoma Phosphorylation N Y580 Q06124 5781 PTPN11 PTP2C SHPTP2 Hiatal hernia Phosphorylation N Y580 Q13616 8454 CUL1 Stomach adenocarcinoma Acetylation N K13 Q13616 8454 CUL1 Head and neck squamous cell carcinoma Phosphorylation N S70 Q13616 8454 CUL1 Head and neck squamous cell carcinoma Methylation N K73 Q13616 8454 CUL1 Head and neck squamous cell carcinoma Ubiquitination N K74 Q13616 8454 CUL1 Head and neck squamous cell carcinoma Phosphorylation N T77 Q13616 8454 CUL1 Bladder urothelial carcinoma Ubiquitination N K290 Q13616 8454 CUL1 Head and neck squamous cell carcinoma Ubiquitination N K290 Q13616 8454 CUL1 Uterine corpus endometrial carcinoma Ubiquitination N K290 Q13616 8454 CUL1 Uterus adenocarcinoma Ubiquitination N K290 Q13616 8454 CUL1 Lung adenocarcinoma Ubiquitination N K410 Q13616 8454 CUL1 Bladder urothelial carcinoma Ubiquitination N K417 Q13616 8454 CUL1 Hepatocellular carcinoma Ubiquitination N K417 Q13616 8454 CUL1 Skin cutaneous melanoma Ubiquitination N K417 Q13616 8454 CUL1 Bladder urothelial carcinoma Phosphorylation N Y425 Q13616 8454 CUL1 Hepatocellular carcinoma Phosphorylation N Y425 Q13616 8454 CUL1 Skin cutaneous melanoma Phosphorylation N Y425 Q13616 8454 CUL1 Cervical squamous cell carcinoma and endocervical adenocarcinoma Acetylation N K431 Q13616 8454 CUL1 Hepatocellular carcinoma Ubiquitination N K464 Q13616 8454 CUL1 Lung adenocarcinoma Ubiquitination N K464 Q13616 8454 CUL1 Renal cell carcinoma Ubiquitination N K464 Q13616 8454 CUL1 Stomach adenocarcinoma Ubiquitination N K464 Q13616 8454 CUL1 Lung adenocarcinoma Ubiquitination N K468 Q13616 8454 CUL1 Renal cell carcinoma Ubiquitination N K468 Q13616 8454 CUL1 Stomach adenocarcinoma Ubiquitination N K468 Q13616 8454 CUL1 Head and neck squamous cell carcinoma Ubiquitination N K493 Q13616 8454 CUL1 Kidney renal clear cell carcinoma Ubiquitination N K493 Q13616 8454 CUL1 Kidney renal papillary cell carcinoma Ubiquitination N K493 Q13616 8454 CUL1 Renal cell carcinoma Ubiquitination N K493 Q13616 8454 CUL1 Stomach adenocarcinoma Ubiquitination N K493 Q13616 8454 CUL1 Breast invasive carcinoma Ubiquitination N K522 Q13616 8454 CUL1 Stomach adenocarcinoma Ubiquitination N K522 Q13616 8454 CUL1 Breast invasive carcinoma Ubiquitination N K708 Q13616 8454 CUL1 Skin cutaneous melanoma Ubiquitination N K708 Q13616 8454 CUL1 Stomach adenocarcinoma Ubiquitination N K708 Q13616 8454 CUL1 Cervical squamous cell carcinoma and endocervical adenocarcinoma Ubiquitination N K720 Q13616 8454 CUL1 Kidney renal papillary cell carcinoma Ubiquitination N K720 Q13616 8454 CUL1 Lung adenocarcinoma Ubiquitination N K720 Q13616 8454 CUL1 Renal cell carcinoma Ubiquitination N K720 Q13616 8454 CUL1 Skin cutaneous melanoma Ubiquitination N K720 Q13616 8454 CUL1 Stomach adenocarcinoma Ubiquitination N K720 Q13616 8454 CUL1 Lung adenocarcinoma Ubiquitination N K751 Q13616 8454 CUL1 Breast cancer breast cancer tissues Neddylation U 38126621 Q13616 8454 CUL1 Pleural mesothelioma MPM cells Neddylation U 35197103 O43818 9136 RRP9 RNU3IP2 U355K Colon cancer colon tissue Deneddylation A K221 34662580 O43818 9136 RRP9 RNU3IP2 U355K Colon cancer colon tissue Neddylation P K221 34662580 P10276 5914 RARA NR1B1 Triple-negative breast cancer TNBC tissues Serine phosphorylation U S77 33902658 P10276 5914 RARA NR1B1 Acute promyelocytic leukemia APL cells Deneddylation A K227 35194189 P10276 5914 RARA NR1B1 Acute promyelocytic leukemia APL cells Neddylation P K227 35194189 P10276 5914 RARA NR1B1 Acute promyelocytic leukemia APL cells Deneddylation A K360 35194189 P10276 5914 RARA NR1B1 Acute promyelocytic leukemia APL cells Neddylation P K360 35194189 Q06124 5781 PTPN11 PTP2C SHPTP2 Colorectal cancer CRC tissues Neddylation D K358 36626230 Q06124 5781 PTPN11 PTP2C SHPTP2 Colorectal cancer CRC tissues Neddylation D K364 36626230 Q13616 8454 CUL1 Hepatocellular carcinoma HCC tissues Deneddylation U 35713976 P10276 5914 RARA NR1B1 Xeroderma pigmentosum HD2 cells Serine phosphorylation N S77 11955452 Q06124 5781 PTPN11 PTP2C SHPTP2 Heart failure HEK293T cells Threonine phosphorylation P T73 25802336 Q06124 5781 PTPN11 PTP2C SHPTP2 Colorectal cancer CRC tissues Deneddylation U K358 36626230 Q06124 5781 PTPN11 PTP2C SHPTP2 Colorectal cancer CRC tissues Deneddylation U K364 36626230 Q06124 5781 PTPN11 PTP2C SHPTP2 Prostate cancer/carcinoma/adenocarcinoma tumor tissue Tyrosine phosphorylation U Y584 22307624 Q06124 5781 PTPN11 PTP2C SHPTP2 Heart failure Serine phosphorylation P S189 25802336 Q06124 5781 PTPN11 PTP2C SHPTP2 Lymphoma Tyrosine phosphorylation U Y584 17483340 Q13616 8454 CUL1 Lymphoma Neddylation U K720 25395170